Alzheimer's disease laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

OR

[Test] is usually normal among patients with [disease name].

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

• There are no diagnostic laboratory findings associated with Alzheimer's disease. However, laboratory findings are done to rule out other conditions which may mimic Alzheimer's disease symptoms. These include:
• Vitamin B12 levels: Patients with low Vitamin B12 levels may present with impaired consciousness and cognition.
• Thyroid hormones: Patients with either low or high T3 may develop altered cognition and sensorium.
• Electrolytes: Serum electrolytes such as hypo or hypernatremia may present with either altered sensorium.
• Complete blood count
• Blood glucose
• Renal function test
• Liver function test
• Drug panel
• CSF analysis for Aβ42 and Tau protein
• CSF evaluation may also be done to rule out syphilis and meningitis

OR

• An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
• [Test] is usually normal among patients with [disease name].
• Laboratory findings consistent with the diagnosis of [disease name] include
  • [Abnormal test 1]
  • [Abnormal test 2]
  • [Abnormal test 3]

• Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].