Alzheimer's disease laboratory findings: Difference between revisions

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There are no specific diagnostic laboratory findings associated with Alzheimer's disease. However, laboratory findings are done to rule out other conditions which may mimic Alzheimer's disease symptoms. These include:
There are no specific diagnostic laboratory findings associated with Alzheimer's disease. However, laboratory findings are done to rule out other conditions which may mimic Alzheimer's disease symptoms. These include:
* CSF analysis for Aβ42 and Tau protein
* CSF analysis for Aβ42 and Tau protein
* CSF analysis for 14-3-3 protein or neuron specific enolase for Creutzfeldt-jakob disease.
* CSF analysis for 14-3-3 protein or neuron specific enolase for Creutzfeldt-jakob disease
* CSF evaluation may also be done to rule out syphilis, encephalitis and meningitis
* CSF evaluation may also be done to rule out syphilis, encephalitis and meningitis
* Vitamin B12 levels: Patients with low Vitamin B12 levels may present with impaired consciousness and cognition.
* Vitamin B12 levels: Patients with low Vitamin B12 levels may present with impaired consciousness and cognition
* Thyroid hormones: Patients with either low or high T3 may develop altered cognition and sensorium.
* Thyroid hormones: Patients with either low or high T3 may develop altered cognition and sensorium
* Electrolytes: Serum electrolytes such as hypo or hypernatremia, hypocalcemia may present with either altered sensorium.
* Electrolytes: Serum electrolytes such as hypo or hypernatremia, hypocalcemia may present with either altered sensorium
* HIV serology or PCR to rule out HIV
* Complete blood count
* Complete blood count
* Blood glucose
* Blood glucose

Revision as of 00:55, 21 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Laboratory Findings

There are no specific diagnostic laboratory findings associated with Alzheimer's disease. However, laboratory findings are done to rule out other conditions which may mimic Alzheimer's disease symptoms. These include:

  • CSF analysis for Aβ42 and Tau protein
  • CSF analysis for 14-3-3 protein or neuron specific enolase for Creutzfeldt-jakob disease
  • CSF evaluation may also be done to rule out syphilis, encephalitis and meningitis
  • Vitamin B12 levels: Patients with low Vitamin B12 levels may present with impaired consciousness and cognition
  • Thyroid hormones: Patients with either low or high T3 may develop altered cognition and sensorium
  • Electrolytes: Serum electrolytes such as hypo or hypernatremia, hypocalcemia may present with either altered sensorium
  • HIV serology or PCR to rule out HIV
  • Complete blood count
  • Blood glucose
  • Renal function test
  • Liver function test
  • Urine screen for drug abuse

References

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