Alzheimer's disease laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
There are no specific diagnostic laboratory findings associated with Alzheimer's disease. However, laboratory findings are done to rule out other conditions which may mimic Alzheimer's disease symptoms. These include: | There are no specific [[diagnostic]] [[laboratory]] findings associated with Alzheimer's disease. However, [[laboratory]] findings are done to rule out other [[conditions]] which may mimic Alzheimer's disease [[symptoms]]. These include: | ||
* [[CSF analysis]] for [[Aβ]] 2 and [[tau protein]] | * [[CSF analysis]] for [[Aβ]] 2 and [[tau protein]] | ||
* [[CSF analysis]] for [[14-3-3 protein]] or neuron specific enolase for [[Creutzfeldt-Jakob disease|Creutzfeldt-jakob disease]] | * [[CSF analysis]] for [[14-3-3 protein]] or neuron specific enolase for [[Creutzfeldt-Jakob disease|Creutzfeldt-jakob disease]] |
Revision as of 01:00, 21 September 2017
Alzheimer's disease Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Laboratory Findings
There are no specific diagnostic laboratory findings associated with Alzheimer's disease. However, laboratory findings are done to rule out other conditions which may mimic Alzheimer's disease symptoms. These include:
- CSF analysis for Aβ 2 and tau protein
- CSF analysis for 14-3-3 protein or neuron specific enolase for Creutzfeldt-jakob disease
- CSF evaluation may also be done to rule out syphilis, encephalitis and meningitis
- Vitamin B12 levels: Patients with low Vitamin B12 levels may present with impaired consciousness and cognition
- Thyroid hormones: Patients with either low or high T3 may develop altered cognition and sensorium
- Electrolytes: Serum electrolytes such as hypo or hypernatremia, hypocalcemia may present with either altered sensorium
- HIV serology or PCR to rule out HIV
- Complete blood count
- Blood glucose
- Renal function test
- Liver function test
- Urine screen for drug abuse