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{{Infobox_gene}}
{{PBB_Controls
'''Syntaxin-2''', also known as '''epimorphin''', is a [[protein]] that in humans is encoded by the ''STX2'' [[gene]].<ref name="pmid8938452">{{cite journal | vauthors = Zha H, Remmers EF, Szpirer C, Szpirer J, Zhang H, Kozak CA, Wilder RL | title = The epimorphin gene is highly conserved among humans, mice, and rats and maps to human chromosome 7, mouse chromosome 5, and rat chromosome 12 | journal = Genomics | volume = 37 | issue = 3 | pages = 386–9 | date = Nov 1996 | pmid = 8938452 | pmc =  | doi = 10.1006/geno.1996.0574 }}</ref><ref name="pmid15943887">{{cite journal | vauthors = Band AM, Kuismanen E | title = Localization of plasma membrane t-SNAREs syntaxin 2 and 3 in intracellular compartments | journal = BMC Cell Biology | volume = 6 | issue = 1 | pages = 26 | date = Jun 2005 | pmid = 15943887 | pmc = 1156879 | doi = 10.1186/1471-2121-6-26 }}</ref><ref name="entrez">{{Cite web| title = Entrez Gene: STX2 syntaxin 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2054| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.<ref name="entrez"/> When the N terminus is on the cytosolic face it acts as a [[t-SNARE]] involved in intracellular vesicle docking and is called Syntaxin-2. When flipped inside out, i.e. N terminus hangs out on the extracellular surface (by some nonclassical secretion pathway) it acts as a versatile [[morphogen]] and is called epimorphin. This membrane protein enjoys the double choice of another form of topological alternatives of being targeted to either apical or basolateral surface of an epithelial cell in a regulated way depending on various contexts. When expressed by mesenchymal cells it can instruct epithelial morphogenesis at epithelial mesenchymal interfaces.
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Syntaxin 2
| HGNCid = 3403
| Symbol = STX2
| AltSymbols =; EPIM; EPM; MGC51014; STX2A; STX2B; STX2C
| OMIM = 132350
| ECnumber = 
| Homologene = 37559
| MGIid = 108059
| GeneAtlas_image1 = PBB_GE_STX2_213434_at_tn.png
| Function = {{GNF_GO|id=GO:0008565 |text = protein transporter activity}}
| Component = {{GNF_GO|id=GO:0005625 |text = soluble fraction}} {{GNF_GO|id=GO:0005792 |text = microsome}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0006886 |text = intracellular protein transport}} {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007398 |text = ectoderm development}} {{GNF_GO|id=GO:0009887 |text = organ morphogenesis}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2054
    | Hs_Ensembl = ENSG00000111450
    | Hs_RefseqProtein = NP_001971
    | Hs_RefseqmRNA = NM_001980
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 12
    | Hs_GenLoc_start = 129840102
    | Hs_GenLoc_end = 129889764
    | Hs_Uniprot = P32856
    | Mm_EntrezGene = 13852
    | Mm_Ensembl = ENSMUSG00000029428
    | Mm_RefseqmRNA = NM_007941
    | Mm_RefseqProtein = NP_031967
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 5
    | Mm_GenLoc_start = 129299275
    | Mm_GenLoc_end = 129323280
    | Mm_Uniprot = Q80W45
  }}
}}
'''Syntaxin 2''', also known as '''STX2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: STX2 syntaxin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2054| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{PBB_Summary
| section_title =  
| summary_text = The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.<ref name="entrez">{{cite web | title = Entrez Gene: STX2 syntaxin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2054| accessdate = }}</ref>
}}


==References==
STX2 has been shown to [[Protein-protein interaction|interact]] with [[SNAP-25]],<ref name=pmid7768895>{{cite journal | vauthors = Hata Y, Südhof TC | title = A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic | journal = The Journal of Biological Chemistry | volume = 270 | issue = 22 | pages = 13022–8 | date = Jun 1995 | pmid = 7768895 | doi = 10.1074/jbc.270.22.13022 }}</ref><ref name=pmid8663154>{{cite journal | vauthors = Ravichandran V, Chawla A, Roche PA | title = Identification of a novel syntaxin- and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues | journal = The Journal of Biological Chemistry | volume = 271 | issue = 23 | pages = 13300–3 | date = Jun 1996 | pmid = 8663154 | doi = 10.1074/jbc.271.23.13300 }}</ref> [[SNAP23]],<ref name=pmid8663154/><ref name=pmid12828989>{{cite journal | vauthors = Imai A, Nashida T, Yoshie S, Shimomura H | title = Intracellular localisation of SNARE proteins in rat parotid acinar cells: SNARE complexes on the apical plasma membrane | journal = Archives of Oral Biology | volume = 48 | issue = 8 | pages = 597–604 | date = Aug 2003 | pmid = 12828989 | doi = 10.1016/S0003-9969(03)00116-X }}</ref><ref name=pmid12651853>{{cite journal | vauthors = Li G, Alexander EA, Schwartz JH | title = Syntaxin isoform specificity in the regulation of renal H+-ATPase exocytosis | journal = The Journal of Biological Chemistry | volume = 278 | issue = 22 | pages = 19791–7 | date = May 2003 | pmid = 12651853 | doi = 10.1074/jbc.M212250200 }}</ref><ref name=pmid9168999>{{cite journal | vauthors = Araki S, Tamori Y, Kawanishi M, Shinoda H, Masugi J, Mori H, Niki T, Okazawa H, Kubota T, Kasuga M | title = Inhibition of the binding of SNAP-23 to syntaxin 4 by Munc18c | journal = Biochemical and Biophysical Research Communications | volume = 234 | issue = 1 | pages = 257–62 | date = May 1997 | pmid = 9168999 | doi = 10.1006/bbrc.1997.6560 }}</ref> [[STXBP1]]<ref name=pmid7768895/><ref name=pmid12773094>{{cite journal | vauthors = Schraw TD, Lemons PP, Dean WL, Whiteheart SW | title = A role for Sec1/Munc18 proteins in platelet exocytosis | journal = The Biochemical Journal | volume = 374 | issue = Pt 1 | pages = 207–17 | date = Aug 2003 | pmid = 12773094 | pmc = 1223584 | doi = 10.1042/BJ20030610 }}</ref> and [[Syntaxin binding protein 3]].<ref name=pmid12773094/>
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal  | author=Hirai Y, Takebe K, Takashina M, ''et al.'' |title=Epimorphin: a mesenchymal protein essential for epithelial morphogenesis. |journal=Cell |volume=69 |issue= 3 |pages= 471-81 |year= 1992 |pmid= 1581962 |doi= }}
*{{cite journal | author=Hata Y, Südhof TC |title=A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. |journal=J. Biol. Chem. |volume=270 |issue= 22 |pages= 13022-8 |year= 1995 |pmid= 7768895 |doi=  }}
*{{cite journal  | author=Li C, Ullrich B, Zhang JZ, ''et al.'' |title=Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. |journal=Nature |volume=375 |issue= 6532 |pages= 594-9 |year= 1995 |pmid= 7791877 |doi= 10.1038/375594a0 }}
*{{cite journal  | author=Hirai Y |title=Molecular cloning of human epimorphin: identification of isoforms and their unique properties. |journal=Biochem. Biophys. Res. Commun. |volume=191 |issue= 3 |pages= 1332-7 |year= 1993 |pmid= 8466509 |doi= 10.1006/bbrc.1993.1363 }}
*{{cite journal  | author=Oka Y, Hirai Y |title=Inductive influences of epimorphin on endothelial cells in vitro. |journal=Exp. Cell Res. |volume=222 |issue= 1 |pages= 189-98 |year= 1996 |pmid= 8549663 |doi= 10.1006/excr.1996.0024 }}
*{{cite journal  | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal | author=Zha H, Remmers EF, Szpirer C, ''et al.'' |title=The epimorphin gene is highly conserved among humans, mice, and rats and maps to human chromosome 7, mouse chromosome 5, and rat chromosome 12. |journal=Genomics |volume=37 |issue= 3 |pages= 386-9 |year= 1997 |pmid= 8938452 |doi= 10.1006/geno.1996.0574 }}
*{{cite journal  | author=Betz A, Okamoto M, Benseler F, Brose N |title=Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin. |journal=J. Biol. Chem. |volume=272 |issue= 4 |pages= 2520-6 |year= 1997 |pmid= 8999968 |doi=  }}
*{{cite journal  | author=Tellam JT, Macaulay SL, McIntosh S, ''et al.'' |title=Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. |journal=J. Biol. Chem. |volume=272 |issue= 10 |pages= 6179-86 |year= 1997 |pmid= 9045631 |doi=  }}
*{{cite journal  | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
*{{cite journal  | author=Koshida S, Hirai Y |title=Identification of cellular recognition sequence of epimorphin and critical role of cell/epimorphin interaction in lung branching morphogenesis. |journal=Biochem. Biophys. Res. Commun. |volume=234 |issue= 2 |pages= 522-5 |year= 1997 |pmid= 9177305 |doi= 10.1006/bbrc.1997.6673 }}
*{{cite journal  | author=Hirai Y, Lochter A, Galosy S, ''et al.'' |title=Epimorphin functions as a key morphoregulator for mammary epithelial cells. |journal=J. Cell Biol. |volume=140 |issue= 1 |pages= 159-69 |year= 1998 |pmid= 9425164 |doi=  }}
*{{cite journal | author=Thomas DM, Ferguson GD, Herschman HR, Elferink LA |title=Functional and biochemical analysis of the C2 domains of synaptotagmin IV. |journal=Mol. Biol. Cell |volume=10 |issue= 7 |pages= 2285-95 |year= 1999 |pmid= 10397765 |doi=  }}
*{{cite journal  | author=Pabst S, Hazzard JW, Antonin W, ''et al.'' |title=Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions. |journal=J. Biol. Chem. |volume=275 |issue= 26 |pages= 19808-18 |year= 2000 |pmid= 10777504 |doi= 10.1074/jbc.M002571200 }}
*{{cite journal | author=Kauppi M, Wohlfahrt G, Olkkonen VM |title=Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 43973-9 |year= 2003 |pmid= 12198139 |doi= 10.1074/jbc.M208315200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Terasaki Y, Fukuda Y, Suga M, ''et al.'' |title=Epimorphin expression in interstitial pneumonia. |journal=Respir. Res. |volume=6 |issue= |pages= 6 |year= 2006 |pmid= 15651999 |doi= 10.1186/1465-9921-6-6 }}
*{{cite journal  | author=Band AM, Kuismanen E |title=Localization of plasma membrane t-SNAREs syntaxin 2 and 3 in intracellular compartments. |journal=BMC Cell Biol. |volume=6 |issue= 1 |pages= 26 |year= 2006 |pmid= 15943887 |doi= 10.1186/1471-2121-6-26 }}
*{{cite journal  | author=Low SH, Vasanji A, Nanduri J, ''et al.'' |title=Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. |journal=Mol. Biol. Cell |volume=17 |issue= 2 |pages= 977-89 |year= 2006 |pmid= 16339081 |doi= 10.1091/mbc.E05-05-0462 }}
}}
{{refend}}


{{protein-stub}}
== References ==
{{WikiDoc Sources}}
{{Reflist}}
 
== Further reading ==
{{Refbegin| 2}}
* {{cite journal | vauthors = Hirai Y, Takebe K, Takashina M, Kobayashi S, Takeichi M | title = Epimorphin: a mesenchymal protein essential for epithelial morphogenesis | journal = Cell | volume = 69 | issue = 3 | pages = 471–81 | date = May 1992 | pmid = 1581962 | doi = 10.1016/0092-8674(92)90448-L }}
* {{cite journal | vauthors = Hata Y, Südhof TC | title = A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic | journal = The Journal of Biological Chemistry | volume = 270 | issue = 22 | pages = 13022–8 | date = Jun 1995 | pmid = 7768895 | doi = 10.1074/jbc.270.22.13022 }}
* {{cite journal | vauthors = Li C, Ullrich B, Zhang JZ, Anderson RG, Brose N, Südhof TC | title = Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins | journal = Nature | volume = 375 | issue = 6532 | pages = 594–9 | date = Jun 1995 | pmid = 7791877 | doi = 10.1038/375594a0 }}
* {{cite journal | vauthors = Hirai Y | title = Molecular cloning of human epimorphin: identification of isoforms and their unique properties | journal = Biochemical and Biophysical Research Communications | volume = 191 | issue = 3 | pages = 1332–7 | date = Mar 1993 | pmid = 8466509 | doi = 10.1006/bbrc.1993.1363 }}
* {{cite journal | vauthors = Oka Y, Hirai Y | title = Inductive influences of epimorphin on endothelial cells in vitro | journal = Experimental Cell Research | volume = 222 | issue = 1 | pages = 189–98 | date = Jan 1996 | pmid = 8549663 | doi = 10.1006/excr.1996.0024 }}
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = Apr 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Betz A, Okamoto M, Benseler F, Brose N | title = Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin | journal = The Journal of Biological Chemistry | volume = 272 | issue = 4 | pages = 2520–6 | date = Jan 1997 | pmid = 8999968 | doi = 10.1074/jbc.272.4.2520 }}
* {{cite journal | vauthors = Tellam JT, Macaulay SL, McIntosh S, Hewish DR, Ward CW, James DE | title = Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4 | journal = The Journal of Biological Chemistry | volume = 272 | issue = 10 | pages = 6179–86 | date = Mar 1997 | pmid = 9045631 | doi = 10.1074/jbc.272.10.6179 }}
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = Apr 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
* {{cite journal | vauthors = Koshida S, Hirai Y | title = Identification of cellular recognition sequence of epimorphin and critical role of cell/epimorphin interaction in lung branching morphogenesis | journal = Biochemical and Biophysical Research Communications | volume = 234 | issue = 2 | pages = 522–5 | date = May 1997 | pmid = 9177305 | doi = 10.1006/bbrc.1997.6673 }}
* {{cite journal | vauthors = Hirai Y, Lochter A, Galosy S, Koshida S, Niwa S, Bissell MJ | title = Epimorphin functions as a key morphoregulator for mammary epithelial cells | journal = The Journal of Cell Biology | volume = 140 | issue = 1 | pages = 159–69 | date = Jan 1998 | pmid = 9425164 | pmc = 2132590 | doi = 10.1083/jcb.140.1.159 }}
* {{cite journal | vauthors = Thomas DM, Ferguson GD, Herschman HR, Elferink LA | title = Functional and biochemical analysis of the C2 domains of synaptotagmin IV | journal = Molecular Biology of the Cell | volume = 10 | issue = 7 | pages = 2285–95 | date = Jul 1999 | pmid = 10397765 | pmc = 25443 | doi = 10.1091/mbc.10.7.2285 }}
* {{cite journal | vauthors = Pabst S, Hazzard JW, Antonin W, Südhof TC, Jahn R, Rizo J, Fasshauer D | title = Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions | journal = The Journal of Biological Chemistry | volume = 275 | issue = 26 | pages = 19808–18 | date = Jun 2000 | pmid = 10777504 | doi = 10.1074/jbc.M002571200 }}
* {{cite journal | vauthors = Kauppi M, Wohlfahrt G, Olkkonen VM | title = Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 46 | pages = 43973–9 | date = Nov 2002 | pmid = 12198139 | doi = 10.1074/jbc.M208315200 }}
* {{cite journal | vauthors = Terasaki Y, Fukuda Y, Suga M, Ikeguchi N, Takeya M | title = Epimorphin expression in interstitial pneumonia | journal = Respiratory Research | volume = 6 | issue = 1 | pages = 6 | year = 2006 | pmid = 15651999 | pmc = 548284 | doi = 10.1186/1465-9921-6-6 }}
* {{cite journal | vauthors = Low SH, Vasanji A, Nanduri J, He M, Sharma N, Koo M, Drazba J, Weimbs T | title = Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity | journal = Molecular Biology of the Cell | volume = 17 | issue = 2 | pages = 977–89 | date = Feb 2006 | pmid = 16339081 | pmc = 1356605 | doi = 10.1091/mbc.E05-05-0462 }}
{{Refend}}
 
{{Vesicular transport proteins}}
 
{{Gene-12-stub}}

Latest revision as of 07:15, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Syntaxin-2, also known as epimorphin, is a protein that in humans is encoded by the STX2 gene.[1][2][3]

The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.[3] When the N terminus is on the cytosolic face it acts as a t-SNARE involved in intracellular vesicle docking and is called Syntaxin-2. When flipped inside out, i.e. N terminus hangs out on the extracellular surface (by some nonclassical secretion pathway) it acts as a versatile morphogen and is called epimorphin. This membrane protein enjoys the double choice of another form of topological alternatives of being targeted to either apical or basolateral surface of an epithelial cell in a regulated way depending on various contexts. When expressed by mesenchymal cells it can instruct epithelial morphogenesis at epithelial mesenchymal interfaces.

Interactions

STX2 has been shown to interact with SNAP-25,[4][5] SNAP23,[5][6][7][8] STXBP1[4][9] and Syntaxin binding protein 3.[9]

References

  1. ↑ Zha H, Remmers EF, Szpirer C, Szpirer J, Zhang H, Kozak CA, Wilder RL (Nov 1996). "The epimorphin gene is highly conserved among humans, mice, and rats and maps to human chromosome 7, mouse chromosome 5, and rat chromosome 12". Genomics. 37 (3): 386–9. doi:10.1006/geno.1996.0574. PMID 8938452.
  2. ↑ Band AM, Kuismanen E (Jun 2005). "Localization of plasma membrane t-SNAREs syntaxin 2 and 3 in intracellular compartments". BMC Cell Biology. 6 (1): 26. doi:10.1186/1471-2121-6-26. PMC 1156879. PMID 15943887.
  3. ↑ 3.0 3.1 "Entrez Gene: STX2 syntaxin 2".
  4. ↑ 4.0 4.1 Hata Y, Südhof TC (Jun 1995). "A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic". The Journal of Biological Chemistry. 270 (22): 13022–8. doi:10.1074/jbc.270.22.13022. PMID 7768895.
  5. ↑ 5.0 5.1 Ravichandran V, Chawla A, Roche PA (Jun 1996). "Identification of a novel syntaxin- and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues". The Journal of Biological Chemistry. 271 (23): 13300–3. doi:10.1074/jbc.271.23.13300. PMID 8663154.
  6. ↑ Imai A, Nashida T, Yoshie S, Shimomura H (Aug 2003). "Intracellular localisation of SNARE proteins in rat parotid acinar cells: SNARE complexes on the apical plasma membrane". Archives of Oral Biology. 48 (8): 597–604. doi:10.1016/S0003-9969(03)00116-X. PMID 12828989.
  7. ↑ Li G, Alexander EA, Schwartz JH (May 2003). "Syntaxin isoform specificity in the regulation of renal H+-ATPase exocytosis". The Journal of Biological Chemistry. 278 (22): 19791–7. doi:10.1074/jbc.M212250200. PMID 12651853.
  8. ↑ Araki S, Tamori Y, Kawanishi M, Shinoda H, Masugi J, Mori H, Niki T, Okazawa H, Kubota T, Kasuga M (May 1997). "Inhibition of the binding of SNAP-23 to syntaxin 4 by Munc18c". Biochemical and Biophysical Research Communications. 234 (1): 257–62. doi:10.1006/bbrc.1997.6560. PMID 9168999.
  9. ↑ 9.0 9.1 Schraw TD, Lemons PP, Dean WL, Whiteheart SW (Aug 2003). "A role for Sec1/Munc18 proteins in platelet exocytosis". The Biochemical Journal. 374 (Pt 1): 207–17. doi:10.1042/BJ20030610. PMC 1223584. PMID 12773094.

Further reading

Retrieved from "https://www.wikidoc.org/index.php?title=STX2&oldid=1415780"