EIF4A3: Difference between revisions

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Latest revision as of 00:25, 31 August 2017

Eukaryotic initiation factor 4A-III is a protein that in humans is encoded by the EIF4A3 gene.^[1]^[2]^[3]

Function

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4A-I and eIF4A-II, two other members of the DEAD box protein family.^[3]

References

↑ Holzmann K, Gerner C, Poltl A, Schafer R, Obrist P, Ensinger C, Grimm R, Sauermann G (Feb 2000). "A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A". Biochem Biophys Res Commun. 267 (1): 339–44. doi:10.1006/bbrc.1999.1973. PMID 10623621.
↑ Chan CC, Dostie J, Diem MD, Feng W, Mann M, Rappsilber J, Dreyfuss G (Jan 2004). "eIF4A3 is a novel component of the exon junction complex". RNA. 10 (2): 200–9. doi:10.1261/rna.5230104. PMC 1370532. PMID 14730019.
↑ ^3.0 ^3.1 "Entrez Gene: EIF4A3 eukaryotic translation initiation factor 4A, isoform 3".

Nagase T, Miyajima N, Tanaka A, et al. (1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi:10.1093/dnares/2.1.37. PMID 7788527.
Li Q, Imataka H, Morino S, et al. (1999). "Eukaryotic Translation Initiation Factor 4AIII (eIF4AIII) Is Functionally Distinct from eIF4AI and eIF4AII". Mol. Cell. Biol. 19 (11): 7336–46. PMC 84727. PMID 10523622.
Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC 1370266. PMID 11991638.
Lee S, Baek M, Yang H, et al. (2002). "Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays". Cancer Lett. 184 (2): 197–206. doi:10.1016/S0304-3835(02)00197-0. PMID 12127692.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Palacios IM, Gatfield D, St Johnston D, Izaurralde E (2004). "An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay". Nature. 427 (6976): 753–7. doi:10.1038/nature02351. PMID 14973490.
Ferraiuolo MA, Lee CS, Ler LW, et al. (2004). "A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay". Proc. Natl. Acad. Sci. U.S.A. 101 (12): 4118–23. doi:10.1073/pnas.0400933101. PMC 384704. PMID 15024115.
Shibuya T, Tange TØ, Sonenberg N, Moore MJ (2004). "eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay". Nat. Struct. Mol. Biol. 11 (4): 346–51. doi:10.1038/nsmb750. PMID 15034551.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Xia Q, Kong XT, Zhang GA, et al. (2005). "Proteomics-based identification of DEAD-box protein 48 as a novel autoantigen, a prospective serum marker for pancreatic cancer". Biochem. Biophys. Res. Commun. 330 (2): 526–32. doi:10.1016/j.bbrc.2005.02.181. PMID 15796914.
Ballut L, Marchadier B, Baguet A, et al. (2005). "The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity". Nat. Struct. Mol. Biol. 12 (10): 861–9. doi:10.1038/nsmb990. PMID 16170325.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Gehring NH, Kunz JB, Neu-Yilik G, et al. (2005). "Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements". Mol. Cell. 20 (1): 65–75. doi:10.1016/j.molcel.2005.08.012. PMID 16209946.
Andersen CB, Ballut L, Johansen JS, et al. (2006). "Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA". Science. 313 (5795): 1968–72. doi:10.1126/science.1131981. PMID 16931718.
You KT, Li LS, Kim NG, et al. (2007). "Selective Translational Repression of Truncated Proteins from Frameshift Mutation-Derived mRNAs in Tumors". PLoS Biol. 5 (5): e109. doi:10.1371/journal.pbio.0050109. PMC 1854916. PMID 17456004.
Zhang Z, Krainer AR (2007). "Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components". Proc. Natl. Acad. Sci. U.S.A. 104 (28): 11574–9. doi:10.1073/pnas.0704946104. PMC 1913901. PMID 17606899.

[pmid10623621-1] Holzmann K, Gerner C, Poltl A, Schafer R, Obrist P, Ensinger C, Grimm R, Sauermann G (Feb 2000). "A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A". Biochem Biophys Res Commun. 267 (1): 339–44. doi:10.1006/bbrc.1999.1973. PMID 10623621.

[pmid14730019-2] Chan CC, Dostie J, Diem MD, Feng W, Mann M, Rappsilber J, Dreyfuss G (Jan 2004). "eIF4A3 is a novel component of the exon junction complex". RNA. 10 (2): 200–9. doi:10.1261/rna.5230104. PMC 1370532. PMID 14730019.

[entrez-3] 3.0 ^3.1 "Entrez Gene: EIF4A3 eukaryotic translation initiation factor 4A, isoform 3".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Eukaryotic initiation factor 4A-III''' is a [[protein]] that in humans is encoded by the ''EIF4A3'' [[gene]].<ref name="pmid10623621">{{cite journal |vauthors=Holzmann K, Gerner C, Poltl A, Schafer R, Obrist P, Ensinger C, Grimm R, Sauermann G | title = A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A | journal = Biochem Biophys Res Commun | volume = 267 | issue = 1 | pages = 339–44 |date=Feb 2000 | pmid = 10623621 | pmc =  | doi = 10.1006/bbrc.1999.1973 }}</ref><ref name="pmid14730019">{{cite journal |vauthors=Chan CC, Dostie J, Diem MD, Feng W, Mann M, Rappsilber J, Dreyfuss G | title = eIF4A3 is a novel component of the exon junction complex | journal = RNA | volume = 10 | issue = 2 | pages = 200–9 |date=Jan 2004 | pmid = 14730019 | pmc = 1370532 | doi =10.1261/rna.5230104  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EIF4A3 eukaryotic translation initiation factor 4A, isoform 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9775| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Function ==
-{{GNF_Protein_box
- | image = PBB_Protein_EIF4A3_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 2hxy.
- | PDB = {{PDB2|2hxy}}, {{PDB2|2hyi}}, {{PDB2|2j0q}}, {{PDB2|2j0s}}, {{PDB2|2j0u}}
- | Name = Eukaryotic translation initiation factor 4A, isoform 3
- | HGNCid = 18683
- | Symbol = EIF4A3
- | AltSymbols =; DDX48; KIAA0111; MGC10862; NUK-34; eIF4AIII; hNMP265
- | OMIM = 608546
- | ECnumber =
- | Homologene = 5602
- | MGIid = 1923731
- | GeneAtlas_image1 = PBB_GE_EIF4A3_201303_at_tn.png
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0008026 |text = ATP-dependent helicase activity}} {{GNF_GO|id=GO:0016787 |text = hydrolase activity}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005681 |text = spliceosome}}
- | Process = {{GNF_GO|id=GO:0006364 |text = rRNA processing}} {{GNF_GO|id=GO:0006397 |text = mRNA processing}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 9775
-    | Hs_Ensembl = ENSG00000141543
-    | Hs_RefseqProtein = NP_055555
-    | Hs_RefseqmRNA = NM_014740
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 17
-    | Hs_GenLoc_start = 75723614
-    | Hs_GenLoc_end = 75735533
-    | Hs_Uniprot = P38919
-    | Mm_EntrezGene = 192170
-    | Mm_Ensembl = ENSMUSG00000025580
-    | Mm_RefseqmRNA = NM_138669
-    | Mm_RefseqProtein = NP_619610
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 11
-    | Mm_GenLoc_start = 119104454
-    | Mm_GenLoc_end = 119116133
-    | Mm_Uniprot = Q3TEZ8
-  }}
-}}
-'''Eukaryotic translation initiation factor 4A, isoform 3''', also known as '''EIF4A3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EIF4A3 eukaryotic translation initiation factor 4A, isoform 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9775| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+This gene encodes a member of the [[DEAD box]] protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative [[RNA helicase]]s. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and [[ribosome]] and [[spliceosome]] assembly. Based on their distribution patterns, some members of this family are believed to be involved in [[embryogenesis]], [[spermatogenesis]], and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors [[EIF4A1|eIF4A-I]] and [[EIF4A2|eIF4A-II]], two other members of the DEAD box protein family.<ref name="entrez" />
-{{PBB_Summary
-| section_title =
-| summary_text = This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.<ref name="entrez">{{cite web | title = Entrez Gene: EIF4A3 eukaryotic translation initiation factor 4A, isoform 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9775| accessdate = }}</ref>
-}}
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
-{{PBB_Further_reading
+*{{cite journal  | author=Nagase T |title=Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1 |journal=DNA Res. |volume=2 |issue= 1 |pages= 37–43 |year= 1995 |pmid= 7788527 |doi=10.1093/dnares/2.1.37  |name-list-format=vanc| author2=Miyajima N  | author3=Tanaka A  | display-authors=3  | last4=Sazuka  | first4=T  | last5=Seki  | first5=N  | last6=Sato  | first6=S  | last7=Tabata  | first7=S  | last8=Ishikawa  | first8=K  | last9=Kawarabayasi  | first9=Y  }}
-| citations =
+*{{cite journal  | author=Li Q |title=Eukaryotic Translation Initiation Factor 4AIII (eIF4AIII) Is Functionally Distinct from eIF4AI and eIF4AII |journal=Mol. Cell. Biol. |volume=19 |issue= 11 |pages= 7336–46 |year= 1999 |pmid= 10523622 |doi=  | pmc=84727  |name-list-format=vanc| author2=Imataka H  | author3=Morino S  | display-authors=3  | last4=Rogers Jr  | first4=GW  | last5=Richter-Cook  | first5=NJ  | last6=Merrick  | first6=WC  | last7=Sonenberg  | first7=N  }}
-*{{cite journal  | author=Nagase T, Miyajima N, Tanaka A, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=2 |issue= 1 |pages= 37-43 |year= 1995 |pmid= 7788527 |doi=  }}
+*{{cite journal  | author=Jurica MS |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=10.1017/S1355838202021088  | pmc=1370266  |name-list-format=vanc| author2=Licklider LJ  | author3=Gygi SR  | display-authors=3  | last4=Grigorieff  | first4=Nikolaus  | last5=Moore  | first5=Melissa J.  }}
-*{{cite journal  | author=Li Q, Imataka H, Morino S, ''et al.'' |title=Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII. |journal=Mol. Cell. Biol. |volume=19 |issue= 11 |pages= 7336-46 |year= 1999 |pmid= 10523622 |doi=  }}
+*{{cite journal  | author=Lee S |title=Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays |journal=Cancer Lett. |volume=184 |issue= 2 |pages= 197–206 |year= 2002 |pmid= 12127692 |doi=10.1016/S0304-3835(02)00197-0  |name-list-format=vanc| author2=Baek M  | author3=Yang H  | display-authors=3  | last4=Bang  | first4=Yung-Jue  | last5=Kim  | first5=Woo Ho  | last6=Ha  | first6=Ji-Hong  | last7=Kim  | first7=Dae-Kee  | last8=Jeoung  | first8=Doo-Il  }}
-*{{cite journal  | author=Holzmann K, Gerner C, Pöltl A, ''et al.'' |title=A human common nuclear matrix protein homologous to eukaryotic translation initiation factor 4A. |journal=Biochem. Biophys. Res. Commun. |volume=267 |issue= 1 |pages= 339-44 |year= 2000 |pmid= 10623621 |doi= 10.1006/bbrc.1999.1973 }}
+*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
-*{{cite journal  | author=Jurica MS, Licklider LJ, Gygi SR, ''et al.'' |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426-39 |year= 2002 |pmid= 11991638 |doi=  }}
+*{{cite journal  |vauthors=Palacios IM, Gatfield D, St Johnston D, Izaurralde E |title=An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay |journal=Nature |volume=427 |issue= 6976 |pages= 753–7 |year= 2004 |pmid= 14973490 |doi= 10.1038/nature02351 }}
-*{{cite journal  | author=Lee S, Baek M, Yang H, ''et al.'' |title=Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays. |journal=Cancer Lett. |volume=184 |issue= 2 |pages= 197-206 |year= 2002 |pmid= 12127692 |doi=  }}
+*{{cite journal  | author=Ferraiuolo MA |title=A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 12 |pages= 4118–23 |year= 2004 |pmid= 15024115 |doi= 10.1073/pnas.0400933101  | pmc=384704  |name-list-format=vanc| author2=Lee CS  | author3=Ler LW  | display-authors=3  | last4=Hsu  | first4=J. L.  | last5=Costa-Mattioli  | first5=M.  | last6=Luo  | first6=M.-J.  | last7=Reed  | first7=R.  | last8=Sonenberg  | first8=N. }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  |vauthors=Shibuya T, Tange TØ, Sonenberg N, Moore MJ |title=eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay |journal=Nat. Struct. Mol. Biol. |volume=11 |issue= 4 |pages= 346–51 |year= 2004 |pmid= 15034551 |doi= 10.1038/nsmb750 }}
-*{{cite journal  | author=Chan CC, Dostie J, Diem MD, ''et al.'' |title=eIF4A3 is a novel component of the exon junction complex. |journal=RNA |volume=10 |issue= 2 |pages= 200-9 |year= 2004 |pmid= 14730019 |doi=  }}
+*{{cite journal  | author=Jin J |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051  |name-list-format=vanc| author2=Smith FD  | author3=Stark C  | display-authors=3  | last4=Wells  | first4=Clark D.  | last5=Fawcett  | first5=James P.  | last6=Kulkarni  | first6=Sarang  | last7=Metalnikov  | first7=Pavel  | last8=O'Donnell  | first8=Paul  | last9=Taylor  | first9=Paul }}
-*{{cite journal  | author=Palacios IM, Gatfield D, St Johnston D, Izaurralde E |title=An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay. |journal=Nature |volume=427 |issue= 6976 |pages= 753-7 |year= 2004 |pmid= 14973490 |doi= 10.1038/nature02351 }}
+*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
-*{{cite journal  | author=Ferraiuolo MA, Lee CS, Ler LW, ''et al.'' |title=A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 12 |pages= 4118-23 |year= 2004 |pmid= 15024115 |doi= 10.1073/pnas.0400933101 }}
+*{{cite journal  | author=Andersen JS |title=Nucleolar proteome dynamics |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207  |name-list-format=vanc| author2=Lam YW  | author3=Leung AK  | display-authors=3  | last4=Ong  | first4=Shao-En  | last5=Lyon  | first5=Carol E.  | last6=Lamond  | first6=Angus I.  | last7=Mann  | first7=Matthias }}
-*{{cite journal  | author=Shibuya T, Tange TØ, Sonenberg N, Moore MJ |title=eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay. |journal=Nat. Struct. Mol. Biol. |volume=11 |issue= 4 |pages= 346-51 |year= 2004 |pmid= 15034551 |doi= 10.1038/nsmb750 }}
+*{{cite journal  | author=Xia Q |title=Proteomics-based identification of DEAD-box protein 48 as a novel autoantigen, a prospective serum marker for pancreatic cancer |journal=Biochem. Biophys. Res. Commun. |volume=330 |issue= 2 |pages= 526–32 |year= 2005 |pmid= 15796914 |doi= 10.1016/j.bbrc.2005.02.181  |name-list-format=vanc| author2=Kong XT  | author3=Zhang GA  | display-authors=3  | last4=Hou  | first4=Xiao-Jin  | last5=Qiang  | first5=Hua  | last6=Zhong  | first6=Ren-Qian }}
-*{{cite journal  | author=Jin J, Smith FD, Stark C, ''et al.'' |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436-50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }}
+*{{cite journal  | author=Ballut L |title=The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity |journal=Nat. Struct. Mol. Biol. |volume=12 |issue= 10 |pages= 861–9 |year= 2005 |pmid= 16170325 |doi= 10.1038/nsmb990  |name-list-format=vanc| author2=Marchadier B  | author3=Baguet A  | display-authors=3  | last4=Tomasetto  | first4=Catherine  | last5=Séraphin  | first5=Bertrand  | last6=Le Hir  | first6=Hervé }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209  |name-list-format=vanc| author2=Venkatesan K  | author3=Hao T  | display-authors=3  | last4=Hirozane-Kishikawa  | first4=Tomoko  | last5=Dricot  | first5=Amélie  | last6=Li  | first6=Ning  | last7=Berriz  | first7=Gabriel F.  | last8=Gibbons  | first8=Francis D.  | last9=Dreze  | first9=Matija }}
-*{{cite journal  | author=Andersen JS, Lam YW, Leung AK, ''et al.'' |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77-83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }}
+*{{cite journal  | author=Gehring NH |title=Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements |journal=Mol. Cell |volume=20 |issue= 1 |pages= 65–75 |year= 2005 |pmid= 16209946 |doi= 10.1016/j.molcel.2005.08.012  |name-list-format=vanc| author2=Kunz JB  | author3=Neu-Yilik G  | display-authors=3  | last4=Breit  | first4=Stephen  | last5=Viegas  | first5=Marcelo H.  | last6=Hentze  | first6=Matthias W.  | last7=Kulozik  | first7=Andreas E. }}
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+*{{cite journal  | author=Andersen CB |title=Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA |journal=Science |volume=313 |issue= 5795 |pages= 1968–72 |year= 2006 |pmid= 16931718 |doi= 10.1126/science.1131981  |name-list-format=vanc| author2=Ballut L  | author3=Johansen JS  | display-authors=3  | last4=Chamieh  | first4=H  | last5=Nielsen  | first5=KH  | last6=Oliveira  | first6=CL  | last7=Pedersen  | first7=JS  | last8=Séraphin  | first8=B  | last9=Le Hir  | first9=H }}
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+*{{cite journal  | author=You KT |title=Selective Translational Repression of Truncated Proteins from Frameshift Mutation-Derived mRNAs in Tumors |journal=PLoS Biol. |volume=5 |issue= 5 |pages= e109 |year= 2007 |pmid= 17456004 |doi= 10.1371/journal.pbio.0050109  | pmc=1854916  |name-list-format=vanc| author2=Li LS  | author3=Kim NG  | display-authors=3  | last4=Kang  | first4=Hyun Ju  | last5=Koh  | first5=Kwi Hye  | last6=Chwae  | first6=Yong-Joon  | last7=Kim  | first7=Kyoung Mi  | last8=Kim  | first8=Yoon Ki  | last9=Park  | first9=Sung Mi }}
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+*{{cite journal  |vauthors=Zhang Z, Krainer AR |title=Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 28 |pages= 11574–9 |year= 2007 |pmid= 17606899 |doi= 10.1073/pnas.0704946104  | pmc=1913901 }}
-*{{cite journal  | author=Gehring NH, Kunz JB, Neu-Yilik G, ''et al.'' |title=Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. |journal=Mol. Cell |volume=20 |issue= 1 |pages= 65-75 |year= 2005 |pmid= 16209946 |doi= 10.1016/j.molcel.2005.08.012 }}
-*{{cite journal  | author=Andersen CB, Ballut L, Johansen JS, ''et al.'' |title=Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA. |journal=Science |volume=313 |issue= 5795 |pages= 1968-72 |year= 2006 |pmid= 16931718 |doi= 10.1126/science.1131981 }}
-*{{cite journal  | author=You KT, Li LS, Kim NG, ''et al.'' |title=Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors. |journal=PLoS Biol. |volume=5 |issue= 5 |pages= e109 |year= 2007 |pmid= 17456004 |doi= 10.1371/journal.pbio.0050109 }}
-*{{cite journal  | author=Zhang Z, Krainer AR |title=Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 28 |pages= 11574-9 |year= 2007 |pmid= 17606899 |doi= 10.1073/pnas.0704946104 }}
-}}
 {{refend}}
-{{protein-stub}}
+{{PDB Gallery|geneid=9775}}
-{{WikiDoc Sources}}
+{{Initiation factors}}

EIF4A3: Difference between revisions

Latest revision as of 00:25, 31 August 2017

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