SLC7A2: Difference between revisions

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Revision as of 06:36, 11 September 2017

Low affinity cationic amino acid transporter 2 is a protein that in humans is encoded by the SLC7A2 gene.^[1]^[2]

References

↑ Hoshide R, Ikeda Y, Karashima S, Matsuura T, Komaki S, Kishino T, Niikawa N, Endo F, Matsuda I (Mar 1997). "Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2)". Genomics. 38 (2): 174–8. doi:10.1006/geno.1996.0613. PMID 8954799.
↑ "Entrez Gene: SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2".

Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
González M, Flores C, Pearson JD, et al. (2005). "Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells". Pflugers Arch. 448 (4): 383–94. doi:10.1007/s00424-004-1261-x. PMID 15064952.
Schnorr O, Suschek CV, Kolb-Bachofen V (2003). "The importance of cationic amino acid transporter expression in human skin". J. Invest. Dermatol. 120 (6): 1016–22. doi:10.1046/j.1523-1747.2003.12139.x. PMID 12787129.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hammermann R, Brunn G, Racké K (2002). "Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4". Amino Acids. 21 (2): 211–9. doi:10.1007/s007260170029. PMID 11665818.
Closs EI, Gräf P, Habermeier A, et al. (1997). "Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties". Biochemistry. 36 (21): 6462–8. doi:10.1021/bi962829p. PMID 9174363.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[pmid8954799-1] Hoshide R, Ikeda Y, Karashima S, Matsuura T, Komaki S, Kishino T, Niikawa N, Endo F, Matsuda I (Mar 1997). "Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2)". Genomics. 38 (2): 174–8. doi:10.1006/geno.1996.0613. PMID 8954799.

[entrez-2] "Entrez Gene: SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2".

[1]

[2]

@@ Line 1: / Line 1: @@
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+{{Underlinked|date=June 2016}}
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+'''Low affinity cationic amino acid transporter 2''' is a [[protein]] that in humans is encoded by the ''SLC7A2'' [[gene]].<ref name="pmid8954799">{{cite journal | vauthors = Hoshide R, Ikeda Y, Karashima S, Matsuura T, Komaki S, Kishino T, Niikawa N, Endo F, Matsuda I | title = Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2) | journal = Genomics | volume = 38 | issue = 2 | pages = 174–8 |date=Mar 1997 | pmid = 8954799 | pmc =  | doi = 10.1006/geno.1996.0613 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6542| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
- | HGNCid = 11060
- | Symbol = SLC7A2
- | AltSymbols =; ATRC2; CAT-2; HCAT2
- | OMIM = 601872
- | ECnumber =
- | Homologene = 20659
- | MGIid = 99828
- | GeneAtlas_image1 = PBB_GE_SLC7A2_207626_s_at_tn.png
- | Function = {{GNF_GO|id=GO:0015174 |text = basic amino acid transmembrane transporter activity}}{{GNF_GO|id=GO:0015179 |text = L-amino acid transmembrane transporter activity}}{{GNF_GO|id=GO:0015359 |text = amino acid transmembrane transporter activity}}
- | Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
-  | Process = {{GNF_GO|id=GO:0006520 |text = amino acid metabolic process}} {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0015807 |text = L-amino acid transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 6542
-    | Hs_Ensembl = ENSG00000003989
-    | Hs_RefseqProtein = NP_001008539
-    | Hs_RefseqmRNA = NM_001008539
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 8
-    | Hs_GenLoc_start = 17440685
-    | Hs_GenLoc_end = 17472296
-    | Hs_Uniprot = P52569
-    | Mm_EntrezGene = 11988
-    | Mm_Ensembl = ENSMUSG00000031596
-    | Mm_RefseqmRNA = NM_001044740
-    | Mm_RefseqProtein = NP_001038205
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 8
-    | Mm_GenLoc_start = 42397761
-    | Mm_GenLoc_end = 42415357
-    | Mm_Uniprot = Q38RA6
-  }}
-}}
-'''Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2''', also known as '''SLC7A2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6542| accessdate = }}</ref>
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 {{PBB_Summary
@@ Line 60: / Line 12: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
@@ Line 66: / Line 18: @@
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
+*{{cite journal   |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406  | pmc=1356129 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=González M, Flores C, Pearson JD, ''et al.'' |title=Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells. |journal=Pflugers Arch. |volume=448 |issue= 4 |pages= 383-94 |year= 2005 |pmid= 15064952 |doi= 10.1007/s00424-004-1261-x }}
+*{{cite journal   |vauthors=González M, Flores C, Pearson JD, etal |title=Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells. |journal=Pflugers Arch. |volume=448 |issue= 4 |pages= 383–94 |year= 2005 |pmid= 15064952 |doi= 10.1007/s00424-004-1261-x }}
-*{{cite journal  | author=Schnorr O, Suschek CV, Kolb-Bachofen V |title=The importance of cationic amino acid transporter expression in human skin. |journal=J. Invest. Dermatol. |volume=120 |issue= 6 |pages= 1016-22 |year= 2003 |pmid= 12787129 |doi= 10.1046/j.1523-1747.2003.12139.x }}
+*{{cite journal  | vauthors=Schnorr O, Suschek CV, Kolb-Bachofen V |title=The importance of cationic amino acid transporter expression in human skin. |journal=J. Invest. Dermatol. |volume=120 |issue= 6 |pages= 1016–22 |year= 2003 |pmid= 12787129 |doi= 10.1046/j.1523-1747.2003.12139.x }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Hammermann R, Brunn G, Racké K |title=Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4. |journal=Amino Acids |volume=21 |issue= 2 |pages= 211-9 |year= 2002 |pmid= 11665818 |doi=  }}
+*{{cite journal  | vauthors=Hammermann R, Brunn G, Racké K |title=Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4. |journal=Amino Acids |volume=21 |issue= 2 |pages= 211–9 |year= 2002 |pmid= 11665818 |doi=10.1007/s007260170029  }}
-*{{cite journal  | author=Closs EI, Gräf P, Habermeier A, ''et al.'' |title=Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. |journal=Biochemistry |volume=36 |issue= 21 |pages= 6462-8 |year= 1997 |pmid= 9174363 |doi= 10.1021/bi962829p }}
+*{{cite journal   |vauthors=Closs EI, Gräf P, Habermeier A, etal |title=Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. |journal=Biochemistry |volume=36 |issue= 21 |pages= 6462–8 |year= 1997 |pmid= 9174363 |doi= 10.1021/bi962829p }}
-*{{cite journal  | author=Hoshide R, Ikeda Y, Karashima S, ''et al.'' |title=Molecular cloning, tissue distribution, and chromosomal localization of human cationic amino acid transporter 2 (HCAT2). |journal=Genomics |volume=38 |issue= 2 |pages= 174-8 |year= 1997 |pmid= 8954799 |doi= 10.1006/geno.1996.0613 }}
 }}
 {{refend}}
 {{NLM content}}
 {{Membrane transport proteins}}
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+{{PBB_Controls
+| update_page = yes
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 [[Category:Solute carrier family]]
-{{WH}}
-{{WS}}
+{{membrane-protein-stub}}

SLC7A2: Difference between revisions

Revision as of 06:36, 11 September 2017

See also

References

Further reading

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