Lung mass screening: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 18: | Line 18: | ||
* Low-dose helical [[computed tomography]]<ref name="lungscreen">Lung Cancer Screening. National Cancer Institute 2015. http://www.cancer.gov/types/lung/hp/lung-screening-pdq Accessed on December 20, 2015</ref> | * Low-dose helical [[computed tomography]]<ref name="lungscreen">Lung Cancer Screening. National Cancer Institute 2015. http://www.cancer.gov/types/lung/hp/lung-screening-pdq Accessed on December 20, 2015</ref> | ||
:* Benefits | :* Benefits: | ||
::* There is evidence that [[screening]] persons aged 55 to 74 years who have cigarette smoking histories of 30 or more pack-years and who, if they are former smokers, have quit within the last 15 years reduces [[lung cancer]] [[mortality]] by 20% and all-cause [[mortality]] by 6.7%. | ::* There is evidence that [[screening]] persons aged 55 to 74 years who have cigarette smoking histories of 30 or more pack-years and who, if they are former smokers, have quit within the last 15 years reduces [[lung cancer]] [[mortality]] by 20% and all-cause [[mortality]] by 6.7%. | ||
:* Harms | :* Harms: | ||
::* The majority of of all positive low-dose helical [[computed tomography]] screening exams do not result in a [[lung cancer]] diagnosis. | ::* The majority of of all positive low-dose helical [[computed tomography]] screening exams do not result in a [[lung cancer]] diagnosis. | ||
::* False-positive exams may result in unnecessary invasive diagnostic procedures. | ::* False-positive exams may result in unnecessary invasive diagnostic procedures. | ||
* [[Chest X-ray|Chest x-ray]] <ref name="JAMA">Davis AM, Cifu AS. Lung Cancer Screening. JAMA. 2014;312(12):1248-1249. doi:10.1001/jama.2014.12272.</ref> | * [[Chest X-ray|Chest x-ray]] <ref name="JAMA">Davis AM, Cifu AS. Lung Cancer Screening. JAMA. 2014;312(12):1248-1249. doi:10.1001/jama.2014.12272.</ref> | ||
:*Benefits | :*Benefits: | ||
::*Screening with [[Chest X-ray|chest x-ray]] does not reduce [[mortality]] from [[lung cancer]] in the general population or in ever-smokers. | ::*Screening with [[Chest X-ray|chest x-ray]] does not reduce [[mortality]] from [[lung cancer]] in the general population or in ever-smokers. | ||
:* Harms | :* Harms: | ||
::* False positive exams | ::* False positive exams. | ||
::* The majority of of all positive [[Chest X-ray|chest x-ray]] [[screening]] exams do not result in a [[lung cancer]] diagnosis. | ::* The majority of of all positive [[Chest X-ray|chest x-ray]] [[screening]] exams do not result in a [[lung cancer]] diagnosis. | ||
::* False-positive exams result in unnecessary invasive diagnostic procedures. | ::* False-positive exams result in unnecessary invasive diagnostic procedures. | ||
Revision as of 21:25, 23 March 2018
|
Lung Mass Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Lung mass screening On the Web |
|
American Roentgen Ray Society Images of Lung mass screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
According to the U.S. Preventive Services Task Force (USPSTF), screening for suspected lung cancer by low-dose computed tomography is recommended every year among smokers who are between 55 to 80 years old and who have history of smoke 30 pack-years or more and either continue to smoke or have quit within the past 15 years (grade B recommendation).[1][2][3][4]
Screening
Guidelines
- According to the U.S. Preventive Services Task Force (USPSTF), screening for suspected lung cancer by low-dose computed tomography is recommended every year among smokers who are between 55 to 80 years old and who have history of smoke 30 pack-years or more and either continue to smoke or have quit within the past 15 years (grade B recommendation).[1][3][4][2]
- According to the clinical practice guideline issued by the American College of Chest Physicians (CHEST) in 2013, screening for suspected lung cancer by low-dose CT (LDCT) is recommended every year among smokers and former smokers who are age 55 to 74 and who have smoked for 30 pack-years or more and either continue to smoke or have quit within the past 15 years.[5]
Strategies
- Low-dose helical computed tomography[6]
- Benefits:
- There is evidence that screening persons aged 55 to 74 years who have cigarette smoking histories of 30 or more pack-years and who, if they are former smokers, have quit within the last 15 years reduces lung cancer mortality by 20% and all-cause mortality by 6.7%.
- Harms:
- The majority of of all positive low-dose helical computed tomography screening exams do not result in a lung cancer diagnosis.
- False-positive exams may result in unnecessary invasive diagnostic procedures.
- Benefits:
- Screening with chest x-ray does not reduce mortality from lung cancer in the general population or in ever-smokers.
- Harms:
- False positive exams.
- The majority of of all positive chest x-ray screening exams do not result in a lung cancer diagnosis.
- False-positive exams result in unnecessary invasive diagnostic procedures.
Overdiagnosis
- Based on current evidence, the majority of lung mass cases detected by screening chest x-ray appear to represent over-diagnosed cancer.[7]
- The magnitude of overdiagnosis appears to be between 5% and 25%.
- These cancers result in unnecessary diagnostic procedures and also lead to unnecessary treatment.
- Harms of diagnostic procedures and treatment occur most frequently among long-term and/or heavy smokers because of smoking-associated comorbidities that increase risk propagation.
References
- ↑ 1.0 1.1 Davis AM, Cifu AS. Lung Cancer Screening. JAMA. 2014;312(12):1248-1249. doi:10.1001/jama.2014.12272.
- ↑ 2.0 2.1 National Lung Screening Trial. Wikipedia. https://en.wikipedia.org/wiki/National_Lung_Screening_Trial Accessed on February 4,2016
- ↑ 3.0 3.1 Recommendations. US preventive services task force(2016) http://www.uspreventiveservicestaskforce.org/BrowseRec/Search?s=solitary_pulmonary_nodule Accessed on March, 15th 2016
- ↑ 4.0 4.1 McWilliams A, Tammemagi MC, Mayo JR, et. al. Probability of cancer in pulmonary nodules detected on first screening CT. N Engl J Med. 2013 Sep 5;369(10):910-9. doi:10.1056/NEJMoa1214726.
- ↑ Detterbeck FC, Mazzone PJ, Naidich DP, Bach PB (2013). "Screening for Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines". Chest. 143 (5 Suppl): e78S–92S. doi:10.1378/chest.12-2350. PMID 23649455. Summary in JournalWatch
- ↑ Lung Cancer Screening. National Cancer Institute 2015. http://www.cancer.gov/types/lung/hp/lung-screening-pdq Accessed on December 20, 2015
- ↑ 7.0 7.1 Davis AM, Cifu AS. Lung Cancer Screening. JAMA. 2014;312(12):1248-1249. doi:10.1001/jama.2014.12272.