Atopic dermatitis causes: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 6: | Line 6: | ||
{{CMG}} | {{CMG}} | ||
== Overview == | == Overview == | ||
Atopic dermatitis (AD) is a chronic inflammatory skin disorder which primarily occurs as a result of various genetics, immune or environmental factors. Other causes leading to development of atopic dematitis include infection, hygiene hypothesis, climate and cigarette smoking. | |||
==Causes== | ==Causes== | ||
Revision as of 18:19, 17 October 2018
|
Atopic dermatitis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Atopic dermatitis causes On the Web |
|
American Roentgen Ray Society Images of Atopic dermatitis causes |
|
Risk calculators and risk factors forAtopic dermatitis causes |
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Atopic dermatitis (AD) is a chronic inflammatory skin disorder which primarily occurs as a result of various genetics, immune or environmental factors. Other causes leading to development of atopic dematitis include infection, hygiene hypothesis, climate and cigarette smoking.
Causes
Common Causes
- Genetics:
- Filaggrin gene encodes proteins which are involved in the epidermal proliferation and differentiation of cytokines.[1]
- Loss-of-function mutations in the filaggrin gene (FLG) causes epidermal barrier dysfunction.
- Infection:
- Atopic dermatitis patient's skin is often colonized by staphylococcus aureus and herpes simplex virus.
- It acts as a superantigen and thought to cause the flare up of atopic dermatitis.
- Hygiene hypothesis:
- According to hygiene hypothesis, reduced early childhood exposure to numerous infectious agents, increases the risk of being susceptible to atopic dermatitis.[2]
- Climate:
- Extreme cold and extreme hot temperature causes flare up of atopic dermatitis.
- Dry weather aggravates xerosis whereas sweating leads to severe pruritus.
- Smoking:
- Current exposure to tobacco may contribute to the adult onset of atopic dermatitis.[3]
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Interferon gamma |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
- List the causes of the disease in alphabetical order. You may need to list across the page, as seen here
References
- ↑ Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen JP, Albrecht E, Baurecht H, Feenstra B, Sleiman PM, Hysi P, Warrington NM, Curjuric I, Myhre R, Curtin JA, Groen-Blokhuis MM, Kerkhof M, Sääf A, Franke A, Ellinghaus D, Fölster-Holst R, Dermitzakis E, Montgomery SB, Prokisch H, Heim K, Hartikainen AL, Pouta A, Pekkanen J, Blakemore AI, Buxton JL, Kaakinen M, Duffy DL, Madden PA, Heath AC, Montgomery GW, Thompson PJ, Matheson MC, Le Souëf P, St Pourcain B, Smith GD, Henderson J, Kemp JP, Timpson NJ, Deloukas P, Ring SM, Wichmann HE, Müller-Nurasyid M, Novak N, Klopp N, Rodríguez E, McArdle W, Linneberg A, Menné T, Nohr EA, Hofman A, Uitterlinden AG, van Duijn CM, Rivadeneira F, de Jongste JC, van der Valk RJ, Wjst M, Jogi R, Geller F, Boyd HA, Murray JC, Kim C, Mentch F, March M, Mangino M, Spector TD, Bataille V, Pennell CE, Holt PG, Sly P, Tiesler CM, Thiering E, Illig T, Imboden M, Nystad W, Simpson A, Hottenga JJ, Postma D, Koppelman GH, Smit HA, Söderhäll C, Chawes B, Kreiner-Møller E, Bisgaard H, Melén E, Boomsma DI, Custovic A, Jacobsson B, Probst-Hensch NM, Palmer LJ, Glass D, Hakonarson H, Melbye M, Jarvis DL, Jaddoe VW, Gieger C, Strachan DP, Martin NG, Jarvelin MR, Heinrich J, Evans DM, Weidinger S (December 2011). "Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis". Nat. Genet. 44 (2): 187–92. doi:10.1038/ng.1017. PMC 3272375. PMID 22197932.
- ↑ Williams, Hywel; Flohr, Carsten (2006). "How epidemiology has challenged 3 prevailing concepts about atopic dermatitis". Journal of Allergy and Clinical Immunology. 118 (1): 209–213. doi:10.1016/j.jaci.2006.04.043. ISSN 0091-6749.
- ↑ Lee CH, Chuang HY, Hong CH, Huang SK, Chang YC, Ko YC, Yu HS (March 2011). "Lifetime exposure to cigarette smoking and the development of adult-onset atopic dermatitis". Br. J. Dermatol. 164 (3): 483–9. doi:10.1111/j.1365-2133.2010.10116.x. PMC 3062947. PMID 21054333.