Atopic dermatitis history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The most common symptoms of atopic dermatitis include pruritus, distribution of [[rash]] on age- specific patters and [[dry skin]]. Patients often have personal or [[family history]] of [[asthma]] or [[allergic rhinitis]]. Patients with atopic dermatitis may report a positive history of cutaneous hyper-reactivity to diverse environmental stimuli and [[Atopy|atopic disorders]]. | The most common symptoms of atopic dermatitis include [[pruritus]], distribution of [[rash]] on age- specific patters and [[dry skin]]. Patients often have personal or [[family history]] of [[asthma]] or [[allergic rhinitis]]. Patients with atopic dermatitis may report a positive history of [[cutaneous]] hyper-reactivity to diverse environmental stimuli and [[Atopy|atopic disorders]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
===History=== | ===History=== | ||
Patients with atopic dermatitis may have a positive history of:<ref name="pmid23712284">{{cite journal |vauthors=Leung DY |title=New insights into atopic dermatitis: role of skin barrier and immune dysregulation |journal=Allergol Int |volume=62 |issue=2 |pages=151–61 |date=June 2013 |pmid=23712284 |doi=10.2332/allergolint.13-RAI-0564 |url=}}</ref><ref name="pmid97349032">{{cite journal |vauthors=Rudikoff D, Lebwohl M |title=Atopic dermatitis |journal=Lancet |volume=351 |issue=9117 |pages=1715–21 |date=June 1998 |pmid=9734903 |doi=10.1016/S0140-6736(97)12082-7 |url=}}</ref> | Patients with atopic dermatitis may have a positive history of:<ref name="pmid23712284">{{cite journal |vauthors=Leung DY |title=New insights into atopic dermatitis: role of skin barrier and immune dysregulation |journal=Allergol Int |volume=62 |issue=2 |pages=151–61 |date=June 2013 |pmid=23712284 |doi=10.2332/allergolint.13-RAI-0564 |url=}}</ref><ref name="pmid97349032">{{cite journal |vauthors=Rudikoff D, Lebwohl M |title=Atopic dermatitis |journal=Lancet |volume=351 |issue=9117 |pages=1715–21 |date=June 1998 |pmid=9734903 |doi=10.1016/S0140-6736(97)12082-7 |url=}}</ref> | ||
*Cutaneous hyper-reactivity to diverse environmental stimuli including: | *[[Cutaneous]] hyper-reactivity to diverse environmental stimuli including: | ||
**Exposure to food and inhalant [[allergens]] | **Exposure to food and inhalant [[allergens]] | ||
**Changes in physical environment (including [[humidity]], [[pollution]] etc) | **Changes in physical environment (including [[humidity]], [[pollution]] etc) | ||
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===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of atopic dermatitis include:<ref name="DeleuranVestergaard2014">{{cite journal|last1=Deleuran|first1=M.|last2=Vestergaard|first2=C.|title=Clinical heterogeneity and differential diagnosis of atopic dermatitis|journal=British Journal of Dermatology|volume=170|year=2014|pages=2–6|issn=00070963|doi=10.1111/bjd.12933}}</ref> | Common symptoms of atopic dermatitis include:<ref name="DeleuranVestergaard2014">{{cite journal|last1=Deleuran|first1=M.|last2=Vestergaard|first2=C.|title=Clinical heterogeneity and differential diagnosis of atopic dermatitis|journal=British Journal of Dermatology|volume=170|year=2014|pages=2–6|issn=00070963|doi=10.1111/bjd.12933}}</ref> | ||
*Severe [[pruritus]] : Can cause [[sleep disturbances]] in children<ref name="pmid7633537">{{cite journal |vauthors=Dahl RE, Bernhisel-Broadbent J, Scanlon-Holdford S, Sampson HA, Lupo M |title=Sleep disturbances in children with atopic dermatitis |journal=Arch Pediatr Adolesc Med |volume=149 |issue=8 |pages=856–60 |date=August 1995 |pmid=7633537 |doi= |url=}}</ref> | *Severe [[pruritus]]: Can cause [[sleep disturbances]] in children<ref name="pmid7633537">{{cite journal |vauthors=Dahl RE, Bernhisel-Broadbent J, Scanlon-Holdford S, Sampson HA, Lupo M |title=Sleep disturbances in children with atopic dermatitis |journal=Arch Pediatr Adolesc Med |volume=149 |issue=8 |pages=856–60 |date=August 1995 |pmid=7633537 |doi= |url=}}</ref> | ||
*Chronic or relapsing skin lesions | *Chronic or relapsing skin lesions | ||
*Distribution of rash on: | *Distribution of rash on: | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shalinder Singh, M.B.B.S.[2]
Overview
The most common symptoms of atopic dermatitis include pruritus, distribution of rash on age- specific patters and dry skin. Patients often have personal or family history of asthma or allergic rhinitis. Patients with atopic dermatitis may report a positive history of cutaneous hyper-reactivity to diverse environmental stimuli and atopic disorders.
History and Symptoms
History
Patients with atopic dermatitis may have a positive history of:[1][2]
- Cutaneous hyper-reactivity to diverse environmental stimuli including:
- Atopic march: Development of clinical signs during childhood from atopic dermatitis to asthma to allergic rhinitis.[3][4][5]
- Cinical features of atopic dermatitis usually occur earlier in life.
- Asthma and allergic rhinitis usually occur later on in life.
Common Symptoms
Common symptoms of atopic dermatitis include:[6]
- Severe pruritus: Can cause sleep disturbances in children[7]
- Chronic or relapsing skin lesions
- Distribution of rash on:
- Facial and extensor surfaces in infants and young children
- Flexural lichenification in older children and adults
Less Common Symptoms
Less common symptoms of atopic dermatitis include:[8]
- Facial pallor
- Dry skin especially in winter)
- Nonspecific dermatitis of the hands and feet
- Food intolerance
- Itch when sweating
References
- ↑ Leung DY (June 2013). "New insights into atopic dermatitis: role of skin barrier and immune dysregulation". Allergol Int. 62 (2): 151–61. doi:10.2332/allergolint.13-RAI-0564. PMID 23712284.
- ↑ Rudikoff D, Lebwohl M (June 1998). "Atopic dermatitis". Lancet. 351 (9117): 1715–21. doi:10.1016/S0140-6736(97)12082-7. PMID 9734903.
- ↑ Spergel JM (August 2010). "From atopic dermatitis to asthma: the atopic march". Ann. Allergy Asthma Immunol. 105 (2): 99–106, quiz 107–9, 117. doi:10.1016/j.anai.2009.10.002. PMID 20674819.
- ↑ Spergel JM (August 2010). "From atopic dermatitis to asthma: the atopic march". Ann. Allergy Asthma Immunol. 105 (2): 99–106, quiz 107–9, 117. doi:10.1016/j.anai.2009.10.002. PMID 20674819.
- ↑ Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H (August 2006). "Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys". Lancet. 368 (9537): 733–43. doi:10.1016/S0140-6736(06)69283-0. PMID 16935684.
- ↑ Deleuran, M.; Vestergaard, C. (2014). "Clinical heterogeneity and differential diagnosis of atopic dermatitis". British Journal of Dermatology. 170: 2–6. doi:10.1111/bjd.12933. ISSN 0007-0963.
- ↑ Dahl RE, Bernhisel-Broadbent J, Scanlon-Holdford S, Sampson HA, Lupo M (August 1995). "Sleep disturbances in children with atopic dermatitis". Arch Pediatr Adolesc Med. 149 (8): 856–60. PMID 7633537.
- ↑ Rudikoff D, Lebwohl M (June 1998). "Atopic dermatitis". Lancet. 351 (9117): 1715–21. doi:10.1016/S0140-6736(97)12082-7. PMID 9734903.