Chondrosarcoma classification: Difference between revisions

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Revision as of 16:42, 22 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Chondrosarcoma may be classified based on histological findings, location and imaging findings (Enneking classification).

Chondrosarcoma be classified based on histological findings, location and imaging findings.

Chondrosarcoma may be classified based on histological findings into following groups:^[1]^[2]

Primary Chondrosarcoma

Chondrosarcoma that arises denovo and comprises of following subtypes:
- Conventional chondrosarcoma - Low-grade, high-grade, and dedifferentiated chondrosarcoma (90% of all chondrosarcomas)
- Clear cell chondrosarcoma (1% of all chondrosarcomas)
- Mesenchymal chondrosarcoma (2% of all chondrosarcomas)

Secondary Chondrosarcoma

Chondrosarcoma may be classified based on location into following groups:^[3]^[4]
- Centrally located within the medullary cavity. (central chondrosarcoma) (70% of all chondrosarcomas)
- Peripherally located on the surface of bone as a result of malignant transformation within the cartilaginous cap. (Peripheral chondrosarcoma) (15% of all chondrosarcomas)

The Enneking surgical staging system (also known as the MSTS system) for malignant musculoskeletal tumors based on radiographic characteristics of the tumor host margin.^[5]
It is widely accepted and routinely used classification.

Stages	Grade	Site	Metastasis

IA	G1: Low grade	T1: Intracompartmental	M0: No metastasis
IB	G1: Low grade	T2: Extracompartmental	M0: No metastasis
IIA	G2: High grade	T1: Intracompartmental	M0: No metastasis
IIB	G2: High grade	T2: Extracompartmental	M0: No metastasis
III	G1 or G2	T1 or T2	M1: Regional or distant metastasis

↑ Raymond E, L'Her P, Jeanbourquin D, Schill H, Jancovici R, Daly JP; et al. (1993). "[Chondrosarcoma of the thoracic wall. Review of the literature apropos of 4 cases]". Rev Pneumol Clin. 49 (1): 19–25. PMID 8378694.
↑ Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). "Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment". Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.
↑ Giuffrida AY, Burgueno JE, Koniaris LG, Gutierrez JC, Duncan R, Scully SP (2009). "Chondrosarcoma in the United States (1973 to 2003): an analysis of 2890 cases from the SEER database". J Bone Joint Surg Am. 91 (5): 1063–72. doi:10.2106/JBJS.H.00416. PMID 19411454.
↑ Skeletal Lesions Interobserver Correlation among Expert Diagnosticians (SLICED) Study Group (2007). "Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones". J Bone Joint Surg Am. 89 (10): 2113–23. doi:10.2106/JBJS.F.01530. PMID 17908885.
↑ Jawad MU, Scully SP (2010). "In brief: classifications in brief: enneking classification: benign and malignant tumors of the musculoskeletal system". Clin Orthop Relat Res. 468 (7): 2000–2. doi:10.1007/s11999-010-1315-7. PMC 2882012. PMID 20333492.

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 {{CMG}}; {{AE}} {{Rohan}}
 ==Overview==
-There is no established system for the classification of [disease name].
+Chondrosarcoma may be classified based on histological findings, location and imaging findings (Enneking classification).
-OR
-[Disease name] may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].
-OR
-[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3].
-[Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].
-OR
-Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.
-OR
-If the staging system involves specific and characteristic findings and features:
-According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].
-OR
-The staging of [malignancy name] is based on the [staging system].
-OR
-There is no established system for the staging of [malignancy name].
 ==Classification==