Chondrosarcoma classification: Difference between revisions
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Chondrosarcoma may be classified based on histological findings and location. | Chondrosarcoma may be classified based on histological findings and location. | ||
==Classification== | ==Classification== | ||
*Chondrosarcoma be classified based on histological findings | *Chondrosarcoma be classified based on [[Histology|histological findings]] and location. | ||
===Histological Classification=== | ===Histological Classification=== | ||
*Chondrosarcoma may be classified based on histological findings into following groups:<ref name="pmid8378694">{{cite journal| author=Raymond E, L'Her P, Jeanbourquin D, Schill H, Jancovici R, Daly JP et al.| title=[Chondrosarcoma of the thoracic wall. Review of the literature apropos of 4 cases]. | journal=Rev Pneumol Clin | year= 1993 | volume= 49 | issue= 1 | pages= 19-25 | pmid=8378694 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8378694 }} </ref><ref name="pmid30559960">{{cite journal| author=Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ| title=Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment. | journal=Clin Sarcoma Res | year= 2018 | volume= 8 | issue= | pages= 23 | pmid=30559960 | doi=10.1186/s13569-018-0110-1 | pmc=6293503 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30559960 }} </ref> | *Chondrosarcoma may be classified based on [[Histological|histological findings]] into following groups:<ref name="pmid8378694">{{cite journal| author=Raymond E, L'Her P, Jeanbourquin D, Schill H, Jancovici R, Daly JP et al.| title=[Chondrosarcoma of the thoracic wall. Review of the literature apropos of 4 cases]. | journal=Rev Pneumol Clin | year= 1993 | volume= 49 | issue= 1 | pages= 19-25 | pmid=8378694 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8378694 }} </ref><ref name="pmid30559960">{{cite journal| author=Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ| title=Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment. | journal=Clin Sarcoma Res | year= 2018 | volume= 8 | issue= | pages= 23 | pmid=30559960 | doi=10.1186/s13569-018-0110-1 | pmc=6293503 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30559960 }} </ref> | ||
'''Primary Chondrosarcoma''' | '''Primary Chondrosarcoma''' | ||
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'''Secondary Chondrosarcoma''' | '''Secondary Chondrosarcoma''' | ||
*Chondrosarcoma that arises from benign cartilage lesions includes (7% of all chondrosarcomas): | *Chondrosarcoma that arises from [[benign]] [[cartilage]] lesions includes (7% of all chondrosarcomas): | ||
**Osteochondroma (<1% risk of malignant transfomation) | **[[Osteochondroma]] (<1% risk of [[malignant]] transfomation) | ||
**Multiple hereditary exostosis (1-10% risk of malignant transformation) | **Multiple hereditary exostosis (1-10% risk of [[malignant]] transformation) | ||
**Enchondromas (1% risk of malignant transformation) | **[[Enchondroma|Enchondromas]] (1% risk of [[malignant]] transformation) | ||
**Ollier's disease (25-40% risk of malignant transformation) | **[[Enchondroma|Ollier's disease]] (25-40% risk of [[malignant]] transformation) | ||
**Maffucci's disease(100% risk of malignant transformation) | **[[Maffucci's disease]](100% risk of [[malignant]] transformation) | ||
===Based on Location=== | ===Based on Location=== | ||
*Chondrosarcoma may be classified based on location into following groups:<ref name="pmid19411454">{{cite journal| author=Giuffrida AY, Burgueno JE, Koniaris LG, Gutierrez JC, Duncan R, Scully SP| title=Chondrosarcoma in the United States (1973 to 2003): an analysis of 2890 cases from the SEER database. | journal=J Bone Joint Surg Am | year= 2009 | volume= 91 | issue= 5 | pages= 1063-72 | pmid=19411454 | doi=10.2106/JBJS.H.00416 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19411454 }} </ref><ref name="pmid17908885">{{cite journal| author=Skeletal Lesions Interobserver Correlation among Expert Diagnosticians (SLICED) Study Group| title=Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones. | journal=J Bone Joint Surg Am | year= 2007 | volume= 89 | issue= 10 | pages= 2113-23 | pmid=17908885 | doi=10.2106/JBJS.F.01530 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17908885 }} </ref> | *Chondrosarcoma may be classified based on location into following groups:<ref name="pmid19411454">{{cite journal| author=Giuffrida AY, Burgueno JE, Koniaris LG, Gutierrez JC, Duncan R, Scully SP| title=Chondrosarcoma in the United States (1973 to 2003): an analysis of 2890 cases from the SEER database. | journal=J Bone Joint Surg Am | year= 2009 | volume= 91 | issue= 5 | pages= 1063-72 | pmid=19411454 | doi=10.2106/JBJS.H.00416 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19411454 }} </ref><ref name="pmid17908885">{{cite journal| author=Skeletal Lesions Interobserver Correlation among Expert Diagnosticians (SLICED) Study Group| title=Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones. | journal=J Bone Joint Surg Am | year= 2007 | volume= 89 | issue= 10 | pages= 2113-23 | pmid=17908885 | doi=10.2106/JBJS.F.01530 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17908885 }} </ref> | ||
**Centrally located within the medullary cavity. (central chondrosarcoma) (70% of all chondrosarcomas) | **Centrally located within the [[medullary cavity]]. (central chondrosarcoma) (70% of all chondrosarcomas) | ||
**Peripherally located on the surface of bone as a result of malignant transformation within the cartilaginous cap. (Peripheral chondrosarcoma) (15% of all chondrosarcomas) | **Peripherally located on the surface of bone as a result of [[malignant]] transformation within the [[cartilaginous]] cap. (Peripheral chondrosarcoma) (15% of all chondrosarcomas) | ||
==References== | ==References== | ||
Latest revision as of 15:52, 24 January 2019
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Chondrosarcoma classification On the Web |
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Risk calculators and risk factors for Chondrosarcoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]
Overview
Chondrosarcoma may be classified based on histological findings and location.
Classification
- Chondrosarcoma be classified based on histological findings and location.
Histological Classification
- Chondrosarcoma may be classified based on histological findings into following groups:[1][2]
Primary Chondrosarcoma
- Chondrosarcoma that arises denovo and comprises of following subtypes:
- Conventional chondrosarcoma - Low-grade, high-grade, and dedifferentiated chondrosarcoma (90% of all chondrosarcomas)
- Clear cell chondrosarcoma (1% of all chondrosarcomas)
- Mesenchymal chondrosarcoma (2% of all chondrosarcomas)
Secondary Chondrosarcoma
- Chondrosarcoma that arises from benign cartilage lesions includes (7% of all chondrosarcomas):
- Osteochondroma (<1% risk of malignant transfomation)
- Multiple hereditary exostosis (1-10% risk of malignant transformation)
- Enchondromas (1% risk of malignant transformation)
- Ollier's disease (25-40% risk of malignant transformation)
- Maffucci's disease(100% risk of malignant transformation)
Based on Location
- Chondrosarcoma may be classified based on location into following groups:[3][4]
- Centrally located within the medullary cavity. (central chondrosarcoma) (70% of all chondrosarcomas)
- Peripherally located on the surface of bone as a result of malignant transformation within the cartilaginous cap. (Peripheral chondrosarcoma) (15% of all chondrosarcomas)
References
- ↑ Raymond E, L'Her P, Jeanbourquin D, Schill H, Jancovici R, Daly JP; et al. (1993). "[Chondrosarcoma of the thoracic wall. Review of the literature apropos of 4 cases]". Rev Pneumol Clin. 49 (1): 19–25. PMID 8378694.
- ↑ Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). "Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment". Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.
- ↑ Giuffrida AY, Burgueno JE, Koniaris LG, Gutierrez JC, Duncan R, Scully SP (2009). "Chondrosarcoma in the United States (1973 to 2003): an analysis of 2890 cases from the SEER database". J Bone Joint Surg Am. 91 (5): 1063–72. doi:10.2106/JBJS.H.00416. PMID 19411454.
- ↑ Skeletal Lesions Interobserver Correlation among Expert Diagnosticians (SLICED) Study Group (2007). "Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones". J Bone Joint Surg Am. 89 (10): 2113–23. doi:10.2106/JBJS.F.01530. PMID 17908885.