Transitional cell carcinoma laboratory findings: Difference between revisions
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{{Transitional cell carcinoma}} | {{Transitional cell carcinoma}} | ||
{{CMG}};{{AE}} {{PSK}} | {{CMG}};{{AE}} {{PSK}} {{Anum}} | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of transitional cell carcinoma include [[blood]] in the [[urine]], abnormal cells in the urine, and elevated [[tumor markers]]. | Laboratory findings consistent with the diagnosis of transitional cell carcinoma include [[blood]] in the [[urine]], abnormal cells in the urine, and elevated [[tumor markers]]. | ||
Revision as of 15:30, 9 July 2019
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Transitional cell carcinoma Microchapters |
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Differentiating Transitional cell carcinoma from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Transitional cell carcinoma laboratory findings On the Web |
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American Roentgen Ray Society Images of Transitional cell carcinoma laboratory findings |
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Directions to Hospitals Treating Transitional cell carcinoma |
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Risk calculators and risk factors for Transitional cell carcinoma laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2] Anum Gull M.B.B.S.[3]
Overview
Laboratory findings consistent with the diagnosis of transitional cell carcinoma include blood in the urine, abnormal cells in the urine, and elevated tumor markers.
Laboratory Findings
- Blood in the urine
- Urine cytology
- Abnormal cells in the urine
- Tumor marker tests: Urine biomarkers could have a significant role in determining which individuals require cystoscopy, as well as determining those who might need evaluation of the upper urinary tract.
- Bladder tumor–associated antigen (BTA)[2]
- Nuclear matrix proteins 22 (NMP)
- NMP52
- Mucin and carcinoembryonic antigen (CEA)
- Hyaluronic acid
- Bladder cancer associated NMP 4 (BLCA-4)
- Survivin
- Cytokeratin (CK) 8 and CK 18
- Low red blood cell count
- Elevated alkaline phosphatase
- UroVysion test is a multicolor FISH assay using probes that can detect aneuploidy of chromosomes 3, 7, or 17 or loss of the 9p21 locus
References
- ↑ Bladder Cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/bladder/diagnosis/?region=ab#urinetest Accessed on October, 6 2015
- ↑ Guo A, Wang X, Gao L, Shi J, Sun C, Wan Z (2014). "Bladder tumour antigen (BTA stat) test compared to the urine cytology in the diagnosis of bladder cancer: A meta-analysis". Can Urol Assoc J. 8 (5–6): E347–52. doi:10.5489/cuaj.1668. PMC 4039599. PMID 24940462.