Autoimmune retinopathy historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
In 1976, the first cases of cancer associated retinopathy (CAR) were observed in three female patients with bronchial carcinoma who developed vision loss with photoreceptor (rods and cones) degeneration. | *In 1976, the first cases of cancer associated retinopathy (CAR) were observed in three female patients with bronchial carcinoma who developed vision loss with photoreceptor (rods and cones) degeneration. | ||
In 1987, 23-kDa retinal antigen, recoverin, targeted by antibodies in the serum of CAR patients was identified by Thirkill and colleague. | *In 1987, 23-kDa retinal antigen, recoverin, targeted by antibodies in the serum of CAR patients was identified by Thirkill and colleague. | ||
In 1997, the first case of autoimmune retinopathy (AIR) was reported in the absence of malignancy with clinical features similar to CAR. Since then, hundreds of cases of paraneoplastic AIR, and non-paraneoplastic AIR have been reported. <ref name="pmid29576753">{{cite journal| author=Sen HN, Grange L, Akanda M, Fox A| title=Autoimmune Retinopathy: Current Concepts and Practices (An American Ophthalmological Society Thesis). | journal=Trans Am Ophthalmol Soc | year= 2017 | volume= 115 | issue= | pages= T8 | pmid=29576753 | doi= | pmc=5844289 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29576753 }} </ref> | *In 1997, the first case of autoimmune retinopathy (AIR) was reported in the absence of malignancy with clinical features similar to CAR. Since then, hundreds of cases of paraneoplastic AIR, and non-paraneoplastic AIR have been reported. <ref name="pmid29576753">{{cite journal| author=Sen HN, Grange L, Akanda M, Fox A| title=Autoimmune Retinopathy: Current Concepts and Practices (An American Ophthalmological Society Thesis). | journal=Trans Am Ophthalmol Soc | year= 2017 | volume= 115 | issue= | pages= T8 | pmid=29576753 | doi= | pmc=5844289 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29576753 }} </ref> | ||
==References== | ==References== | ||
Revision as of 05:22, 17 July 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
Overview
Historical Perspective
- In 1976, the first cases of cancer associated retinopathy (CAR) were observed in three female patients with bronchial carcinoma who developed vision loss with photoreceptor (rods and cones) degeneration.
- In 1987, 23-kDa retinal antigen, recoverin, targeted by antibodies in the serum of CAR patients was identified by Thirkill and colleague.
- In 1997, the first case of autoimmune retinopathy (AIR) was reported in the absence of malignancy with clinical features similar to CAR. Since then, hundreds of cases of paraneoplastic AIR, and non-paraneoplastic AIR have been reported. [1]