ABCC13: Difference between revisions
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==References== | ==References== | ||
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==Further reading== | ==Further reading== | ||
Revision as of 13:50, 4 September 2012
| ATP-binding cassette, sub-family C (CFTR/MRP), member 13 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | ABCC13 ; C21orf73; PRED6 | ||||||||||
| External IDs | Template:OMIM5 | ||||||||||
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| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
ATP-binding cassette, sub-family C (CFTR/MRP), member 13, also known as ABCC13, is a human gene.[1] This gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi-drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. Alternative splicing results in multiple transcript variants; however, not all variants have been fully described.[1]
See also
- ATP-binding cassette transporter
- ABCC13+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
References
Further reading
- Dean M, Annilo T (2005). "Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates". Annual review of genomics and human genetics. 6: 123–42. doi:10.1146/annurev.genom.6.080604.162122. PMID 16124856.
- Annilo T, Dean M (2005). "Degeneration of an ATP-binding cassette transporter gene, ABCC13, in different mammalian lineages". Genomics. 84 (1): 34–46. doi:10.1016/j.ygeno.2004.02.010. PMID 15203202.
- Hillman RT, Green RE, Brenner SE (2005). "An unappreciated role for RNA surveillance". Genome Biol. 5 (2): R8. doi:10.1186/gb-2004-5-2-r8. PMID 14759258.
- Brun ME, Ruault M, Ventura M; et al. (2003). "Juxtacentromeric region of human chromosome 21: a boundary between centromeric heterochromatin and euchromatic chromosome arms". Gene. 312: 41–50. PMID 12909339.
- Yabuuchi H, Takayanagi S, Yoshinaga K; et al. (2003). "ABCC13, an unusual truncated ABC transporter, is highly expressed in fetal human liver". Biochem. Biophys. Res. Commun. 299 (3): 410–7. PMID 12445816.
- Gardiner K, Slavov D, Bechtel L, Davisson M (2002). "Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis". Genomics. 79 (6): 833–43. doi:10.1006/geno.2002.6782. PMID 12036298.
- Hattori M, Fujiyama A, Taylor TD; et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953.
- Allikmets R, Gerrard B, Hutchinson A, Dean M (1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database". Hum. Mol. Genet. 5 (10): 1649–55. PMID 8894702.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.