Chondrosarcoma medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Chemotherapy and radiotherapy are indicated for chondrosarcoma as adjuvant therapy. Proton therapy[1] is a new kind of radiotherapy showing promising results with local tumor control at over 80%.
Medical Therapy
- Chemotherapy or traditional radiotherapy are not very effective for most chondrosarcomas.
- Proton therapy is showing promise with local tumor control at over 80%.[2]
- Proton therapy Radiation can be useful in rare locations such as skull base, spine, rib cage, or larynx to make surgery more effective.
- Recent studies have shown that induction of apoptosis in high-grade chondrosarcoma, both directly and by enhancement of response to chemotherapy and radiation, is a valid therapeutic strategy