Transitional cell carcinoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

History

When evaluating a patient for transitional carcinoma, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough past medical history review. Other specific areas of focus when obtaining the history are:

• Review of smoking history
• Using pain medicines such as phenacetin for a long time

Common Symptoms

• Clinical presentation is variable and usually non-specific.
• Tumors may also result in obstruction and symptomatic hydronephrosis.
• Occasionally there may be no symptoms in the early stages and present once systemic symptoms of metastatic disease are present.

Symptoms of transitional cell carcinoma may include:

Transitional Cell Carcinoma of Bladder

• Hematuria
• Urinary frequency
• Urinary urgency
• Difficulty urinating
• Dysuria

Transitional Cell Carcinoma of Pelvis and Ureter

• Hematuria
• Pain in the flank or abdomen

Less Common Symptoms

• Loss of appetite
• Weight loss
• Fatigue
• Fever
• Change in bowel habits
• Urine leakage (incontinence)
• Pain in the rectum, anus, pelvis, flank above the pubic bone, or in bones
• Lump in the pelvis
• Swelling in the legs, scrotum, or vulva