Transitional cell carcinoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History
When evaluating a patient for transitional cell carcinoma, you should take a detailed history of the presenting symptom (duration, onset, progression), other associated symptoms, and a thorough past medical history review. Other specific areas of focus when obtaining the history are:[1]
- Review of smoking history
- Using pain medicines such as phenacetin for a long time
- Any occupational or environmental risk factors such as being around dyes and chemicals used in making leather, textiles, rubber, or plastics
Common Symptoms
- Clinical presentation is variable and usually non-specific.
- Tumors may also result in obstruction and symptomatic hydronephrosis.
- Occasionally there may be no symptoms in the early stages and present once systemic symptoms of metastatic disease are present.
Symptoms of transitional cell carcinoma may include:[1][2][3]
Transitional Cell Carcinoma of Bladder
- Hematuria
- Urinary frequency
- Urinary urgency
- Difficulty urinating
- Dysuria
Transitional Cell Carcinoma of Pelvis and Ureter
- Hematuria
- Pain in the flank or abdomen
Less Common Symptoms
- Loss of appetite
- Weight loss
- Fatigue
- Fever
- Change in bowel habits
- Urine leakage (incontinence)
- Pain in the rectum, anus, pelvis, flank above the pubic bone, or in bones
- Lump in the pelvis
- Swelling in the legs, scrotum, or vulva
References
- ↑ 1.0 1.1 Risk factors for brain and spinal cord cancer. Canadian Cancer Society(2015) http://www.cancer.ca/en/cancer-information/cancer-type/renal-pelvis-and-ureter/diagnosis/?region=ab Accessed on February, 17 2016
- ↑ Transitional cell cancer. National cancer institute. http://www.cancer.gov/types/kidney/patient/transitional-cell-treatment-pdq
- ↑ Kirkali, Ziya; Tuzel, Emre (2003). "Transitional cell carcinoma of the ureter and renal pelvis". Critical Reviews in Oncology/Hematology. 47 (2): 155–169. doi:10.1016/S1040-8428(03)00079-9. ISSN 1040-8428.