Chondrosarcoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Overview

The most common symptoms of chondrosarcoma include pain and swelling in the area of tumor.

History and Symptoms

  • The symptoms of chondrosarcoma include:[1][2][3][4]
    • Local swelling
    • Palpable mass
    • Pain which is insidious in onset, progressive, worse at night; and usually present for months to years before presentation.
    • Pathologic fracture
    • If chondrosarcoma involves the skull, then patient may present with headache
    • If the lesion is near a neurovascular bundle, the patient may present with nerve dysfunction such as weakness, numbness or tingling.
    • If a chondrosarcoma is close to a joint, it may decrease the joint’s range of motion.

Common Symptoms

Common symptoms of chondrosarcoma include:

  • Local swelling
  • Palpable mass
  • Pain

Less Common Symptoms

Less common symptoms of chondrosarcoma include:

  • Pathologic fracture
  • Headache
  • Nerve dysfunction such as weakness, numbness or tingling
  • Decreased joint’s range of motion

References

  1. Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
  3. Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). "Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment". Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.
  4. Skeletal Lesions Interobserver Correlation among Expert Diagnosticians (SLICED) Study Group (2007). "Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones". J Bone Joint Surg Am. 89 (10): 2113–23. doi:10.2106/JBJS.F.01530. PMID 17908885.

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