Chondrosarcoma surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Overview

Surgery is the mainstay of treatment for chondrosarcoma. Adjunctive chemotherapy and radiation may be required.

Surgery

• Surgery is the mainstay of treatment for chondrosarcoma.

intra-lesional curettage indications Grade 1 lesions in the extremities (minimal rate of metastasis) treatment of grade 1 lesions located in the pelvis or axial skeleton is controversial (higher rate of local recurrence and metastasis) most authors recommend wide excision of all chondrosarcomas (even grade 1) if located in the pelvis wide surgical excision indications grade 2 or 3 lesions grade 1 lesions in pelvis wide surgical excision combined with multi-agent chemotherapy indications mesenchymal chondrosarcoma the role of chemotherapy in de-differentiated chondrosarcoma is very controversial

Recurrence Rate

Grade 1 chondrosarcoma

• It is rare after wide resection with negative margins.
• 5-15% is the recurrence rate after curettage with adjuvant treatment.

Grade 2 chondrosarcoma

• The recurrence rate varies depending on resection margins.

Grade 3 chondrosarcoma

• The local recurrence rate is 25% and >30% chances of metastasis.