Spina bifida diagnostic study of choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Study of choice

Ultrasound is the imaging modality of choice for characterisation of the open spina bifida spinal lesions. On two and tree-dimensional ultrasound, spina bifida is characterized by: Vertebral defect, splayed vertebral pedicles and disrupted vertebrae. The ultrasound must be performed when a positive alpha-fetoprotein is detected in the triple screening test between the 15th and 20th week of pregnancy to confirm the diagnosis.

Diagnostic Study of Choice

Study of choice

  • Ultrasound is the imaging modality of choice for characterisation of the open spina bifida spinal lesions.[1]
  • On two and tree-dimensional ultrasound, spina bifida is characterized by:[2]
Sequence of Diagnostic Studies

The ultrasound must be performed when a positive alpha-fetoprotein is detected in the triple screening test between the 15th and 20th week of pregnancy to confirm the diagnosis.

References

  1. Trudell AS, Odibo AO (April 2014). "Diagnosis of spina bifida on ultrasound: always termination?". Best Pract Res Clin Obstet Gynaecol. 28 (3): 367–77. doi:10.1016/j.bpobgyn.2013.10.006. PMID 24373566.
  2. Lee W, Chaiworapongsa T, Romero R, Williams R, McNie B, Johnson A, Treadwell M, Comstock CH (June 2002). "A diagnostic approach for the evaluation of spina bifida by three-dimensional ultrasonography". J Ultrasound Med. 21 (6): 619–26. PMID 12054297.

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