Peutz-Jeghers syndrome physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Common physical examination findings of Peutz-Jeghers syndrome include mucocutaneous hyperpigmentation, abdominal tenderness due to intussusception, bowel obstruction, and pallor due to anemia.
Physical Examination
Appearance of the Patient
- If cancer develops, patient may appear cachectic
Vitals
Temperature
- Fever may be present, if cancer develops
Respiratory Rate
- Tachypnea may be present, if lung cancer develops
Skin
- Jaundice may be present, if pancreatic cancer develops
Eyes
- Icteric sclera may be present
Throat
- Oral mucosa
- Mucocutaneous pigmentation causing patches of hyperpigmentation in the oral mucosa (gingiva, hard palate, buccal mucosa, and labial mucosa)
Neck
- Lymph nodes may be present, if cancer develops
Lungs
- If lung cancer develops, the patient may present with the following:
- Pulmonary edema and rales may be present
- Wheezing may be present
- Consolidation may be present with reduced breath sounds on auscultation
- Rales may be present
- Egophony may be present
- Chest movement may be asymmetric
Abdomen
- Abdominal distention may be present
- Abdominal tenderness may be present
- Rebound tenderness may be present
- An acute abdomen may be present, if intussusception develops
- An abdominal mass may be present, if hepatic or pancreatic cancers develop
- Guarding may be present
- Hepatomegaly may be present, if hepatic cancer develops
Extremities
- Patches of hyperpigmentation on the hands and feet
- Clubbing may be present, if lung cancer develops
- Cyanosis may be present, if lung cancer develops
