Syndrome of inappropriate antidiuretic hormone medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Treatment of syndrome of inappropriate antidiuretic hormone depends on the etiology. For immediate improvement, all patients with SIADH require sharp restriction of their daily water intake and depending on the sodium levels, 3%hypertonic saline,loop diuretics with normal saline may be used. In emergency settings,Vasopressin-2 receptor antagonists (aquaretics, such as conivaptan or tolvaptan) are used. The most definitive way to treat SIADH is to deal with the underlying problem itself. If SIADH produced by drugs, then the patient must stop taking the medicine. If some infection may be the cause, the patient needs to controlling them by some antibiotics or other anti-microbiological drugs.