Amenorrhea differential diagnosis

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Patient Information Primary amenorrhea Secondary amenorrhea
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Differential Diagnosis Organized by Category of Causes

Physiologic
Hypothalamic
- Structural
  Craniopharyngioma
  
  Lymphoma
  
  Sarcoidosis
  
  Hemochromatosis
- Functional
  Anorexia/bulimia
  
  Excessive exercise/weight loss
  
  Stress
Pituitary
- Secretory tumors
  Prolactinoma
  
  Cushing’s disease
  
  Acromegaly
- Destructive lesions
  Non-functional tumors
  
  Sheehan's syndrome
  
  Hemochromatosis
Ovarian
- Premature ovarian failure
- Hyperandrogenic disorders
  Polycystic ovary syndrome (PCOS)
  
  Nonclassical congenital adrenal hyperplasia (NCCAH)
  
  Adrenal/ovarian androgen-secreting tumors
Anatomic
- Destruction of uterine cavity
  Asherman’s syndrome
  
  Tuberculosis (TB)
Other
- Hyperthyroidism/hypothyroidism
- Cushing’s syndrome