Syndrome of inappropriate antidiuretic hormone epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Syndrome of inappropriate antidiuretic hormone (SIADH) can occur at any age. Its incidence depends upon various possible etiologies. Prevalence of SIADH was estimated to be 2500-3000 cases per 100,000 individuals. The incidence and prevalence of SIADH in particular is less thoroughly studied in the literature.
Epidemiology and Demographics
Prevalence
- Prevalence of SIADH was estimated to be 2500-3000 cases per 100,000 individuals.
- Prevalence of hyponatremia in the United States has been estimated to be 1720 per 100,000 individuals.[1]
Incidence
- SIADH is the most common cause of hyponatremia.[2]
- Incidence of moderate and severe hyponatraemia in the United States ranges from a low of 1000 to 7000 per 100,000 among hospitalized patients.[3]
Age
Gender
- The prevalence and incidence of SIADH does not vary by gender.
Race
- There is no racial predilection to SIADH.
Mortality
- Hospitalized patients with plasma sodium concentration <125 mmol/l show an overall mortality of 28000 per 100,000 patients.[6]
References
- ↑ Mohan S, Gu S, Parikh A, Radhakrishnan J (2013). "Prevalence of hyponatremia and association with mortality: results from NHANES". Am. J. Med. 126 (12): 1127–37.e1. doi:10.1016/j.amjmed.2013.07.021. PMC 3933395. PMID 24262726.
- ↑ O'Donoghue D, Trehan A (2009). "SIADH and hyponatraemia: foreword". NDT Plus. 2 (Suppl_3): iii1–iii4. doi:10.1093/ndtplus/sfp152. PMC 2762825. PMID 19881931.
- ↑ O'Donoghue D, Trehan A (2009). "SIADH and hyponatraemia: foreword". NDT Plus. 2 (Suppl_3): iii1–iii4. doi:10.1093/ndtplus/sfp152. PMC 2762825. PMID 19881931.
- ↑ Tarif N, Sabir O, Niaz A, Akhtar R, Rafique K, Rizvi N (2016). "Hyponatraemia: Epidemiology and aetiology in a tertiary care centre in Pakistan". J Pak Med Assoc. 66 (11): 1436–1439. PMID 27812063.
- ↑ Flear CT, Gill GV, Burn J (1981). "Hyponatraemia: mechanisms and management". Lancet. 2 (8236): 26–31. PMID 6113402.
- ↑ Gill, Geoffrey; Huda, Bobby; Boyd, Alice; Skagen, Karolina; Wile, David; Watson, Ian; van Heyningen, Charles (2006). "Characteristics and mortality of severe hyponatraemia ? a hospital-based study". Clinical Endocrinology. 65 (2): 246–249. doi:10.1111/j.1365-2265.2006.02583.x. ISSN 0300-0664.