Transitional cell carcinoma other imaging findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
CT urography may be diagnostic of transitional cell carcinoma. Findings on CT urography suggestive of upper urinary tract transitional cell carcinoma include filling defect within the renal collecting system, distortion, obliteration, or amputation of calices, and stipple sign.[1]
Other Imaging Fidings
CT Urography
- CT urography (CT IVP) has largely replaced conventional plain film urography and is the mainstay of both diagnosis and staging of transitional cell carcinoma with sensitivity (96%) and specificity (99%).
- All imaging modalities which outline the collecting system with contrast rely on the same possible findings:
- Filling defect
- Distortion, obliteration, or amputation of calices
- In addition an obstructive lesion may lead to hydronephrosis and/or non-functioning kidney (not necessarily with hydronephrosis).
- When tumours are large and of papillary morphology, contrast filling the interstices between papillary projections can lead to a dappled appearance referred to as the stipple sign. This if more commonly seen in the bladder when tumours have room to grow to larger dimensions.
- A calyx may be distended by a tumor within it (known as an oncocalyx) or prevented from filling with contrast (known as a phantom calyx).
References
- ↑ Kirkali, Ziya; Tuzel, Emre (2003). "Transitional cell carcinoma of the ureter and renal pelvis". Critical Reviews in Oncology/Hematology. 47 (2): 155–169. doi:10.1016/S1040-8428(03)00079-9. ISSN 1040-8428.