SLC36A1

Solute carrier family 36 (proton/amino acid symporter), member 1
Identifiers
Symbols	SLC36A1 ; PAT1; LYAAT1; TRAMD3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 70571
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SLC36A1 213119 at tn.png
File:PBB GE SLC36A1 gnf1h01641 at tn.png
File:PBB GE SLC36A1 gnf1h01642 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Solute carrier family 36 (proton/amino acid symporter), member 1, also known as SLC36A1, is a human gene.

This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.

See also

• Solute carrier family

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.CS1 maint: Multiple names: authors list (link)
• Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Simpson JC, Wellenreuther R, Poustka A; et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sagné C, Agulhon C, Ravassard P; et al. (2001). "Identification and characterization of a lysosomal transporter for small neutral amino acids". Proc. Natl. Acad. Sci. U.S.A. 98 (13): 7206–11. doi:10.1073/pnas.121183498. PMID 11390972.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Boll M, Foltz M, Rubio-Aliaga I; et al. (2002). "Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters". J. Biol. Chem. 277 (25): 22966–73. doi:10.1074/jbc.M200374200. PMID 11959859.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen Z, Fei YJ, Anderson CM; et al. (2003). "Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2". J. Physiol. (Lond.). 546 (Pt 2): 349–61. PMID 12527723.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wreden CC, Johnson J, Tran C; et al. (2003). "The H+-coupled electrogenic lysosomal amino acid transporter LYAAT1 localizes to the axon and plasma membrane of hippocampal neurons". J. Neurosci. 23 (4): 1265–75. PMID 12598615.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Boll M, Foltz M, Rubio-Aliaga I, Daniel H (2004). "A cluster of proton/amino acid transporter genes in the human and mouse genomes". Genomics. 82 (1): 47–56. PMID 12809675.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bermingham JR, Pennington J (2004). "Organization and expression of the SLC36 cluster of amino acid transporter genes". Mamm. Genome. 15 (2): 114–25. PMID 15058382.
• Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Anderson CM, Grenade DS, Boll M; et al. (2004). "H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat". Gastroenterology. 127 (5): 1410–22. PMID 15521011.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Anderson CM, Thwaites DT (2005). "Indirect regulation of the intestinal H+-coupled amino acid transporter hPAT1 (SLC36A1)". J. Cell. Physiol. 204 (2): 604–13. doi:10.1002/jcp.20337. PMID 15754324.
• Abbot EL, Grenade DS, Kennedy DJ; et al. (2006). "Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1". Br. J. Pharmacol. 147 (3): 298–306. doi:10.1038/sj.bjp.0706557. PMID 16331283.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kuan YH, Gruebl T, Soba P; et al. (2007). "PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2". J. Biol. Chem. 281 (52): 40114–23. doi:10.1074/jbc.M605407200. PMID 17050537.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.