SLC26A7
| Solute carrier family 26, member 7 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SLC26A7 ; MGC126268; SUT2 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 13770 | ||||||||||
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| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Solute carrier family 26, member 7, also known as SLC26A7, is a human gene.[1]
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Splice variants that use both alternate transcription initiation and polyadenylation sites have been described for this gene.[1]
See also
References
Further reading
- Markovich D (2001). "Physiological roles and regulation of mammalian sulfate transporters". Physiol. Rev. 81 (4): 1499–533. PMID 11581495.
- Vincourt JB, Jullien D, Kossida S; et al. (2002). "Molecular cloning of SLC26A7, a novel member of the SLC26 sulfate/anion transporter family, from high endothelial venules and kidney". Genomics. 79 (2): 249–56. doi:10.1006/geno.2002.6689. PMID 11829495.
- Lohi H, Kujala M, Makela S; et al. (2002). "Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9". J. Biol. Chem. 277 (16): 14246–54. doi:10.1074/jbc.M111802200. PMID 11834742.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Petrovic S, Ju X, Barone S; et al. (2003). "Identification of a basolateral Cl-/HCO3- exchanger specific to gastric parietal cells". Am. J. Physiol. Gastrointest. Liver Physiol. 284 (6): G1093–103. doi:10.1152/ajpgi.00454.2002. PMID 12736153.
- Petrovic S, Barone S, Xu J; et al. (2004). "SLC26A7: a basolateral Cl-/HCO3- exchanger specific to intercalated cells of the outer medullary collecting duct". Am. J. Physiol. Renal Physiol. 286 (1): F161–9. doi:10.1152/ajprenal.00219.2003. PMID 12965893.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Barone S, Amlal H, Xu J; et al. (2004). "Differential regulation of basolateral Cl-/HCO3- exchangers SLC26A7 and AE1 in kidney outer medullary collecting duct". J. Am. Soc. Nephrol. 15 (8): 2002–11. doi:10.1097/01.ASN.0000135060.83250.07. PMID 15284286.
- Kujala M, Tienari J, Lohi H; et al. (2006). "SLC26A6 and SLC26A7 anion exchangers have a distinct distribution in human kidney". Nephron Exp. Nephrol. 101 (2): e50–8. doi:10.1159/000086345. PMID 15956810.
- Xu J, Worrell RT, Li HC; et al. (2006). "Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion". J. Am. Soc. Nephrol. 17 (4): 956–67. doi:10.1681/ASN.2005111174. PMID 16524946.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.