Chondrosarcoma natural history
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Overview
Complications that can develop as a result of chondrosarcoma are metastasis and recurrence. The prognosis of chondrosarcoma is good with treatment. Chondrosarcoma is associated with a 5 year survival rate of 75%. The presence of grade 3 lesions are associated with a particularly poor prognosis.
Complications
- Chondrosarcoma may cause metastasis to other organs.
- Lung is the most common location for metastatic disease.
- Chondrosarcoma may return and may need treatment with surgery, chemotherapy or radiation. Unlike other cancers, chondrosarcoma can return many years later.
Prognosis
- Generally, chondrosarcoma carries a good prognosis.
- Chondrosarcoma is associated with a 5 year survival rate of 75%.
- Depending upon the subtype, prognosis vary substantially:
- Chondrosarcoma NOS: 70% 5 year survival.
- Myxoid chondrosarcoma: 70% 5 year survival.
- Mesenchymal chondrosarcoma: 50% 5 year survival.
- Dedifferentiated chondrosarcoma: 10% 5 year survival.
- Prognosis varies with grade:
- Grade 1: 90% 5 year survival.
- Grade 3: 29% 5 year survival
- Prognosis varies with location:
- long bones have a better prognosis than axial skeleton.