Alzheimer's disease risk factors
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
The most potent risk factors for the development of Alzheimer's dementia (AD) are age and
Risk Factors
The following are the risk factors leading to the development of Alzheimer's dementia (AD):
- Age
- Gender
- Early-life negative events and physical attributes
- Literacy and education
- APOE ε4 is a risk factor for AD among women but not men in Venezuela
- Late onset APOE gene mutation associated Alzheimers's dementia (AD) is affected by the following factors:
- Ethnicity
- Age
- Sex
- Medical history
- Geographical location (Central African Republic, East Africa, Southern Africa, Malaysia, Australia, and Papua New Guinea)
- Stroke
- Vascular disease
- Diet (fruits, vegetables, and fibre decrease risk; Tofu, cycad fruit, salivary phytooestrogens e.g. genistein and daidizein are associated with increased risk)