Alzheimer's disease laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

OR

[Test] is usually normal among patients with [disease name].

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

There are no specific diagnostic laboratory findings associated with Alzheimer's disease. However, laboratory findings are done to rule out other conditions which may mimic Alzheimer's disease symptoms. These include:

• CSF analysis for Aβ42 and Tau protein
• CSF evaluation may also be done to rule out syphilis and meningitis
• Vitamin B12 levels: Patients with low Vitamin B12 levels may present with impaired consciousness and cognition.
• Thyroid hormones: Patients with either low or high T3 may develop altered cognition and sensorium.
• Electrolytes: Serum electrolytes such as hypo or hypernatremia may present with either altered sensorium.
• Complete blood count
• Blood glucose
• Renal function test
• Liver function test
• Urine screen for drug abuse

OR

• An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
• [Test] is usually normal among patients with [disease name].
• Laboratory findings consistent with the diagnosis of [disease name] include
  • [Abnormal test 1]
  • [Abnormal test 2]
  • [Abnormal test 3]

• Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].