Atopic dermatitis secondary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shalinder Singh, M.B.B.S.[2]
Overview
Primary prevention applies to the patients with diagnosed atopic dermatits. Its main goal is to reducing the severity of presentation of skin lesions as well as the use of medical therapy in treating atopic dermatitis.
Secondary Prevention
- Epidermal barrier
- Positive association between damage to the epidermis and severity of atopic dermatitis.[1]
- Increased skin permeability and skin pH due to defective barrier function can lead to colonization by staphylococcus aureus. Restoration of skin barrier function is an important factor for protection from colonization by this pathogen.[2]
- Itching cause scratching which leads to dysfunction of the epidermal skin barrier.
- Risk factors which aggravate itching include sweating, dry skin, emotional stress, hot water, and certain foods.
- Stress can result into increased levels of glucocorticosteroids in blood, which further leads to dysfunction of skin barrier by affecting the integrity and adhesion of the stratum corneum.[3]
- To protect and restore the epidermal skin barrier function[4]
- Patients should abstain from using soap, cosmetics, dyes, fragrances and detergents.
- Wash new clothes before wearing them.
- Keep air temperature around 18–22°C.
- Avoid frequent and sudden climate changes.
- Use air humidifiers in winters.
- Avoid excessive exposure to UV radiations and use SPF sunscreens.
- Application of emollients every 6 h.
- Stress-reducing therapy
References
- ↑ Cork MJ, Danby SG, Vasilopoulos Y, Hadgraft J, Lane ME, Moustafa M, Guy RH, Macgowan AL, Tazi-Ahnini R, Ward SJ (August 2009). "Epidermal barrier dysfunction in atopic dermatitis". J. Invest. Dermatol. 129 (8): 1892–908. doi:10.1038/jid.2009.133. PMID 19494826.
- ↑ Cho JS, Xuan C, Miller LS (December 2010). "Lucky number seven: RNase 7 can prevent Staphylococcus aureus skin colonization". J. Invest. Dermatol. 130 (12): 2703–6. doi:10.1038/jid.2010.294. PMID 21068735.
- ↑ Arndt J, Smith N, Tausk F (July 2008). "Stress and atopic dermatitis". Curr Allergy Asthma Rep. 8 (4): 312–7. PMID 18606083.
- ↑ Oszukowska M, Michalak I, Gutfreund K, Bienias W, Matych M, Szewczyk A, Kaszuba A (December 2015). "Role of primary and secondary prevention in atopic dermatitis". Postepy Dermatol Alergol. 32 (6): 409–20. doi:10.5114/pdia.2014.44017. PMC 4697018. PMID 26755903.