Transitional cell carcinoma MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
MRI findings of transitional cell carcinoma of renal pelvis include isointense to renal parenchyma on T1 and T2, moderate enhancement on T1 contrast. MRI findings of transitional cell carcinoma of bladder and ureter include isotense to muscle on T1 signal, slightly hyperintense to muscle on T2 signal, and demonstrate enhancement on contrast MRI.
MRI
- MRI is as reliable as CT for staging of invasive or locally advanced disease and may be better at evaluating tumors at the base and dome of the bladder.
- Gadolinium-enhanced MRI may be superior to CT to detect superficial and multiple tumors, extravesical tumor extension, and surrounding organ invasion.[1][2]
- MRI is useful for patients with contrast dye allergy
- . Findings on MRI diagnostic of transitional cell carcinoma include:[3]
| Signal | Renal Pelvis | Ureter | Urinary Bladder |
|---|---|---|---|
|
T1 Signal |
Isointense to renal parenchyma |
Isointense to muscle |
Isointense to muscle |
|
T2 Signal |
Isointense to renal parenchyma |
Slightly hyperintense to muscle |
Slightly hyperintense to muscle |
|
T1 C+ (Gd): |
Moderate enhancement |
Enhancement |
Enhancement |
References
- ↑ Tekes A, Kamel I, Imam K, Szarf G, Schoenberg M, Nasir K; et al. (2005). "Dynamic MRI of bladder cancer: evaluation of staging accuracy". AJR Am J Roentgenol. 184 (1): 121–7. doi:10.2214/ajr.184.1.01840121. PMID 15615961.
- ↑ Kim B, Semelka RC, Ascher SM, Chalpin DB, Carroll PR, Hricak H (1994). "Bladder tumor staging: comparison of contrast-enhanced CT, T1- and T2-weighted MR imaging, dynamic gadolinium-enhanced imaging, and late gadolinium-enhanced imaging". Radiology. 193 (1): 239–45. doi:10.1148/radiology.193.1.8090898. PMID 8090898.
- ↑ Browne, Ronan F. J.; Meehan, Conor P.; Colville, Jane; Power, Raymond; Torreggiani, William C. (2005). "Transitional Cell Carcinoma of the Upper Urinary Tract: Spectrum of Imaging Findings1". RadioGraphics. 25 (6): 1609–1627. doi:10.1148/rg.256045517. ISSN 0271-5333.