Dextrocardia epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [[2]]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Claudia Hochberg, M.D.; Assistant Editor-In-Chief: Kristin Feeney, B.S. [[5]]
Overview
Dextrocardia is categorized as a fairly rare disease. The reported likelihood of occurrence is roughly 1 in 100 births with approximately 1 in 1,000 of these cases to have dextrocardia and situs inversus.
Epidemiology and Demographics
Dextrocardia is believed to occur in approximately 1 in a 100 people, while 1 in 1,000 of these will have Situs Inversus. The most recent statistics place the incidence of stitus inversus to be 1:2500 to 1:20,000. It is significantly less common to have dextrocardia with situs solitus.
Kartagener’s syndrome occurs in approximately 1 in 15-25 of patients with Totalis (situs inversus with dextrocardia). Kartagener Syndrome (KS), is a rare autosomal recessive genetic disorder caused by a defect in the action of the tiny hairs (cilia) lining the respiratory tract. Specifically, it is a defect in a gene coding for left-right dynein (lrd), a key structural protein in cilia.[1]
Incidence
- The incidence of dextrocardia is approximately 1 in 12,000 pregnancies.[2]
Prevalence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- There is no racial predilection to [disease name].
- [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
Gender
- Dextrocardia affects men and women equally.[3]
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ Cleveland JC Jr, Shroyer AL, Chen AY, et al: Off-pump coronary artery bypass grafting decreases risk-adjusted mortality and morbidity. Ann Thorac Surg 2001;72: 1282-1289.
- ↑ Bohun CM, Potts JE, Casey BM, Sandor GG (2007). "A population-based study of cardiac malformations and outcomes associated with dextrocardia". Am J Cardiol. 100 (2): 305–9. doi:10.1016/j.amjcard.2007.02.095. PMID 17631088.
- ↑ Mozayan C, Levis JT (2019). "ECG Diagnosis: Dextrocardia". Perm J. 23. doi:10.7812/TPP/18.244. PMC 6730946 Check
|pmc=value (help). PMID 31496498.