Docosanol
| File:Docosan-1-ol.svg | |
| Clinical data | |
|---|---|
| Synonyms | benehic alcohol, benehyl alcohol, docosyl alcohol, n-docosanol |
| Pregnancy category |
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| Routes of administration | Topical |
| ATC code | |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | Not absorbed |
| Metabolism | N/A |
| Elimination half-life | N/A |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| DrugBank | |
| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C22H46O |
| Molar mass | 326.6 g/mol |
| Melting point | 71 °C (159.8 °F) |
| Boiling point | 180 °C (356 °F) |
Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent viral replication.
Abreva is the brand name of a cream containing 10% Docosanol. Abreva is the first over-the-counter anti-viral drug approved for sale in the United States and Canada.
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