Chronic renal failure pathophysiology
Chronic renal failure Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Chronic renal failure pathophysiology On the Web |
American Roentgen Ray Society Images of Chronic renal failure pathophysiology |
Risk calculators and risk factors for Chronic renal failure pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
- Glomerular Disease
- Diagnostic Features
- Red Blood Cell (RBC) casts
- Proteinuria > 3.5 g/d
- Systemic disease associated with glomerulopathy
- Biopsy often needed for definitive diagnosis of nondiabetic glomerular disease
- Clinical diagnosis diabetic nephropathy
- Suggested by duration of Diabetes Mellitus (DM)
- (7-8 years type II, 12-15 years type I),
- Coexistent retinopathy, progressive
- Nephrotic range proteinuria
- Primary Glomerular Disorders
- Secondary Glomerular Disorders
- Diabetic nephropathy
- Lupus nephritis
- Immunoglobulin A (IgA) nephropathy
- Goodpasture’s syndrome
- Amyloidosis
- Diagnostic Features
- Interstitial Disease or Vascular Disease
- Diagnostic Features:
- Bland urinalysis
- Protein excretion < 2-3 g/d
- No glomerulopathy-associated systemic disease
- Interstitial disorders
- Polycystic kidney disease (PCKD)
- Analgesic abuse
- Autoimmune disorders (sarcoidosis, Sjogren’s)
- Vesicoureteral reflux
- Nephrolithiasis
- Obstructive uropathy
- Vascular disorders
- Renal artery stenosis (bilateral)
- Hypertensive nephrosclerosis (can--chronic insterstitial nephritis)
- Vasculitis
- Scleroderma
- Diagnostic Features: