Chronic renal failure screening
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Chronic renal failure Microchapters |
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Risk calculators and risk factors for Chronic renal failure screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Overview
The burden of Chronic renal disease is not only limited to its implications for replacement therapy like dialysis or organ transplant, but also has an impact on overall population health and costs. Infact, patients with Chronic renal disease include the ones who are at risk for progression of renal disease and development of overt end stage renal disease, and a far greater likelihood of cardiovascular disease.
Hence, the objective of screening in these patients is early detection of asymptomatic disease when intervention has a reasonable potential to have an impact on the outcome.
Screening
Currently, screening for chronic renal failure, is only accepted in patients with diabetes and hypertension. Some of the tests frequently used for screening are as follows:
- Serum creatinine levels
- Dipstick urine for proteinuria and hematuria
- GFR estimation
- Urine albumin : creatinine ratio [1] [2]
Various antibody based screening tests are also available, but not used routinely as they require expensive laboratory facilities.
- Radioimmune essay
- Nephelometry
- Immunoturbidimetry
- ELISA [1]
References
- ↑ 1.0 1.1 Perico N, Bravo RF, De Leon FR, Remuzzi G (2009). "Screening for chronic kidney disease in emerging countries: feasibility and hurdles". Nephrol. Dial. Transplant. 24 (5): 1355–8. doi:10.1093/ndt/gfp039. PMID 19218536. Unknown parameter
|month=ignored (help) - ↑ Hallan SI, Dahl K, Oien CM; et al. (2006). "Screening strategies for chronic kidney disease in the general population: follow-up of cross sectional health survey". BMJ. 333 (7577): 1047. doi:10.1136/bmj.39001.657755.BE. PMC 1647344. PMID 17062598. Unknown parameter
|month=ignored (help)