Ferroportin

solute carrier family 40 (iron-regulated transporter), member 1
Identifiers
Symbol	SLC40A1
Alt. symbols	SLC11A3 FPN1
Entrez	30061
HUGO	10909
OMIM	604653
RefSeq	NM_014585
UniProt	Q9NP59
Other data
Locus	Chr. 2 q32

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List of terms related to Ferroportin

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Ferroportin is a transmembrane protein that transports iron from the inside of a cell to the outside of it. It is found on the surface of cells that store or transport iron, including:

• Enterocytes in the duodenum
• Hepatocytes
• Macrophages of the reticuloendothelial system.

Recent research suggests that ferroportin is the key molecule regulated by hepcidin, the apparent "master regulator" of human iron metabolism.

Clinical significance

Ferroportin can be associated with African iron overload.

External links

• ferroportin1+protein at the US National Library of Medicine Medical Subject Headings (MeSH)