SLC4A5

Solute carrier family 4, sodium bicarbonate cotransporter, member 5
Identifiers
Symbols	SLC4A5 ; MGC129662; NBC4
External IDs	Template:OMIM5 Template:MGI HomoloGene: 71686
Gene ontology Molecular function Template:GNF GOTemplate:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SLC4A5 221723 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Solute carrier family 4, sodium bicarbonate cotransporter, member 5, also known as SLC4A5, is a human gene.

This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

See also

• SLC4A5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

Further reading

• Soleimani M, Burnham CE (2002). "Na+:HCO(3-) cotransporters (NBC): cloning and characterization". J. Membr. Biol. 183 (2): 71–84. PMID 11562789.
• Hunt SC, Xin Y, Wu LL; et al. (2006). "Sodium bicarbonate cotransporter polymorphisms are associated with baseline and 10-year follow-up blood pressures". Hypertension. 47 (3): 532–6. doi:10.1161/01.HYP.0000196949.26088.3c. PMID 16365189.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xu J, Wang Z, Barone S; et al. (2003). "Expression of the Na+-HCO-3 cotransporter NBC4 in rat kidney and characterization of a novel NBC4 variant". Am. J. Physiol. Renal Physiol. 284 (1): F41–50. doi:10.1152/ajprenal.00055.2002. PMID 12388414.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pushkin A, Abuladze N, Newman D; et al. (2002). "Genomic organization of the DCTN1-SLC4A5 locus encoding both NBC4 and p150(Glued)". Cytogenet. Cell Genet. 95 (3–4): 163–8. PMID 12063394.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sassani P, Pushkin A, Gross E; et al. (2002). "Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter". Am. J. Physiol., Cell Physiol. 282 (2): C408–16. doi:10.1152/ajpcell.00409.2001. PMID 11788353.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pushkin A, Abuladze N, Newman D; et al. (2001). "Two C-terminal variants of NBC4, a new member of the sodium bicarbonate cotransporter family: cloning, characterization, and localization". IUBMB Life. 50 (1): 13–9. PMID 11087115.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pushkin A, Abuladze N, Newman D; et al. (2000). "Cloning, characterization and chromosomal assignment of NBC4, a new member of the sodium bicarbonate cotransporter family". Biochim. Biophys. Acta. 1493 (1–2): 215–8. PMID 10978526.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.