SLC5A8
| Solute carrier family 5 (iodide transporter), member 8 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SLC5A8 ; AIT; MGC125354; SMCT | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 64832 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SLC5A8 gnf1h02682 at tn.png | |||||||||||
| File:PBB GE SLC5A8 gnf1h06296 at tn.png | |||||||||||
| File:PBB GE SLC5A8 gnf1h06297 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Solute carrier family 5 (iodide transporter), member 8, also known as SLC5A8, is a human gene.[1]
See also
References
Further reading
- Gupta N, Martin PM, Prasad PD, Ganapathy V (2006). "SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter". Life Sci. 78 (21): 2419–25. doi:10.1016/j.lfs.2005.10.028. PMID 16375929.
- Rodriguez AM, Perron B, Lacroix L; et al. (2002). "Identification and characterization of a putative human iodide transporter located at the apical membrane of thyrocytes". J. Clin. Endocrinol. Metab. 87 (7): 3500–3. PMID 12107270.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Li H, Myeroff L, Smiraglia D; et al. (2003). "SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers". Proc. Natl. Acad. Sci. U.S.A. 100 (14): 8412–7. doi:10.1073/pnas.1430846100. PMID 12829793.
- Miyauchi S, Gopal E, Fei YJ, Ganapathy V (2004). "Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids". J. Biol. Chem. 279 (14): 13293–6. doi:10.1074/jbc.C400059200. PMID 14966140.
- Lacroix L, Pourcher T, Magnon C; et al. (2004). "Expression of the apical iodide transporter in human thyroid tissues: a comparison study with other iodide transporters". J. Clin. Endocrinol. Metab. 89 (3): 1423–8. PMID 15001644.
- Hong C, Maunakea A, Jun P; et al. (2005). "Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8". Cancer Res. 65 (9): 3617–23. doi:10.1158/0008-5472.CAN-05-0048. PMID 15867356.
- Paroder V, Spencer SR, Paroder M; et al. (2006). "Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT". Proc. Natl. Acad. Sci. U.S.A. 103 (19): 7270–5. doi:10.1073/pnas.0602365103. PMID 16670197.
- Hu S, Liu D, Tufano RP; et al. (2006). "Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer". Int. J. Cancer. 119 (10): 2322–9. doi:10.1002/ijc.22110. PMID 16858683.
- Gopal E, Miyauchi S, Martin PM; et al. (2007). "Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract". Pharm. Res. 24 (3): 575–84. doi:10.1007/s11095-006-9176-1. PMID 17245649.
- Coady MJ, Wallendorff B, Bourgeois F; et al. (2007). "Establishing a definitive stoichiometry for the Na+/monocarboxylate cotransporter SMCT1". Biophys. J. 93 (7): 2325–31. doi:10.1529/biophysj.107.108555. PMID 17526579.