Chronic renal failure causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]

Overview

Common causes of chronic renal failure include diabetic nephropathy, hypertension, and glomerulonephritis. The commonest cause of stage 5 CKD in the U.S. is diabetes and is characterized by proteinuria and bilaterally enlarged kidneys. Hypertension is the second most common cause of Stage 5 CKD in the US, and often co-exists in diabetic patients.

Causes of CKD

Several conditions, exposures, and drugs can lead to renal injury with progression to CKD. The following list is a summary of most etiologies of CKD:

Conditions: Alport's syndrome Amyloidosis Balkan endemic nephropathy Benign prostatic hyperplasia Chronic Glomerulonephritis Chronic Pyelonephritis Cystinosis Diabetic nephropathy Glomerulosclerosis Goodpasture’s syndrome Hemolytic uremic syndrome Hyperoxaluria Hypertensive nephrosclerosis IgA nephropathy Interstitial Nephritis Light chain disease Lupus nephritis Malignant hypertension Medullary cystic kidney disease Medullary sponge kidney Membranoproliferative Glomerulonephritis Membranous nephritis Metastatic prostate cancer Multiple Myeloma Nephrolithiasis Nephrosclerosis Nephrotic Syndrome Nephritic Syndrome Normocytic normochromic anemia Obstructive uropathy Oxalosis Papillorenal syndrome Polycystic kidney disease Proteinuria Prostate cancer Pyelonephritis Reflux nephropathy Renal artery stenosis Renal cell carcinoma Renal vein thrombosis Renal tubular acidosis Rheumatoid arthritis Scleroderma Sepsis Sickle cell disease Systemic sclerosis Thrombotic thrombocytopenic purpura Renal tubular acidosis Vasculitis Vesicoureteral reflux Wegener's granulomatosis Drugs Acetominophen Acyclovir Allopurinol Aminoglycosides Angiotensin-converting enzyme inhibitors Aspirin Bevacizumab Bismuth Carboplatin Carmustine Chloroquine Cisplatin Cyclosporine Erythromycin Furosemide Gentamicin Hydroxychloroquine NSAIDs Protease Inhibitors Infliximab Laxatives Lithium Lomustine Methicillin Mesalamine Mitomycin C Interferons Nitrosoureas Pamidronate Penicillin Pentamidine Phenytoin Propylthiouracil Quinine Rifampicin Sulfa-containing antibiotics Sulfonamides Tacrolimus Thiazides Vancomycin References Template:WH Template:WS