Piperidione: Difference between revisions

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{{drugbox
{{Drugbox
| IUPAC_name       = 3,3-diethylpiperidine-2,4-dione
| Verifiedfields = changed
| image             = Piperidione.png
| verifiedrevid = 464207558
| width =120px
| IUPAC_name = 3,3-diethylpiperidine-2,4-dione
| CAS_number        =  
| image = Piperidione.png
| ATC_prefix        = R05
| width = 120px
| ATC_suffix        = DB23
| image2 = Piperidione ball-and-stick.png
| PubChem          = 6465
| width2 = 180px
| DrugBank          =
 
| C=9|H=15|N=1|O=2
<!--Clinical data-->
| molecular_weight  = 169.221 g/mol
| tradename = Ascron, Dihyprylon, Dihyprylone, Sedulon, Tusseval
| bioavailability  =  
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| protein_bound    =
| pregnancy_US = <!-- A / B            / C / D / X -->
| metabolism        =
| pregnancy_category =   
| elimination_half-life =
| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| excretion        =  
| legal_CA = <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
| pregnancy_AU     = <!-- A / B1 / B2 / B3 / C / D / X -->
| legal_UK = <!-- GSL        / P      / POM / CD / Class A, B, C -->
| pregnancy_US     = <!-- A / B            / C / D / X -->
| legal_US = <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| pregnancy_category=   
| legal_status =
| legal_AU         = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
| routes_of_administration =
| legal_CA         = <!--            / Schedule I, II, III, IV, V, VI, VII, VIII -->
 
| legal_UK         = <!-- GSL        / P      / POM / CD / Class A, B, C -->
<!--Pharmacokinetic data-->
| legal_US         = <!-- OTC                  / Rx-only  / Schedule I, II, III, IV, V -->
| bioavailability = 
| legal_status     =  
| protein_bound = 
| routes_of_administration =  
| metabolism = 
| elimination_half-life = 
| excretion = 
 
<!--Identifiers-->
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 77-03-2
| ATC_prefix = R05
| ATC_suffix = DB23
| PubChem = 6465
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = 
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 6222
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = BZ6KL0Q8UD
 
<!--Chemical data-->
| C=9 | H=15 | N=1 | O=2
| molecular_weight = 169.221 g/mol
| smiles = O=C1C(C(=O)NCC1)(CC)CC
| InChI = 1/C9H15NO2/c1-3-9(4-2)7(11)5-6-10-8(9)12/h3-6H2,1-2H3,(H,10,12)
| InChIKey = RGEVWUKXWFOAID-UHFFFAOYAK
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C9H15NO2/c1-3-9(4-2)7(11)5-6-10-8(9)12/h3-6H2,1-2H3,(H,10,12)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RGEVWUKXWFOAID-UHFFFAOYSA-N
}}
}}
'''Piperidione''' is a [[cough suppressant]].
'''Piperidione''' (trade name '''Sedulon''') is a [[sedative]] drug, structurally related to [[methyprylon]] and [[pyrithyldione]].
It was previously marketed by Roche as a [[cough suppressant]] available in liquid form.<ref>{{cite pmid|15409516}}</ref><ref>{{cite pmid|18102053}}</ref><ref>{{cite pmid|3839404}}</ref>


{{pharmacology-stub}}
==See also==
*[[Methyprylon]]
*[[Pyrithyldione]]
*[[Glutethimide]]


==References==
{{reflist}}


{{Cough and cold preparations}}
{{Cough and cold preparations}}
{{Hypnotics and sedatives}}
{{GABAAR PAMs}}


[[Category:Antitussives]]
[[Category:Antitussives]]
[[Category:Nitrogen heterocycles]]
[[Category:Piperidines]]
[[Category:Lactams]]
[[Category:Ketones]]
[[Category:GABAA receptor positive allosteric modulators]]
[[Category:Sedatives]]
 
 
{{respiratory-system-drug-stub}}

Revision as of 20:21, 10 April 2015

Piperidione
Clinical data
Trade namesAscron, Dihyprylon, Dihyprylone, Sedulon, Tusseval
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC9H15NO2
Molar mass169.221 g/mol
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Piperidione (trade name Sedulon) is a sedative drug, structurally related to methyprylon and pyrithyldione. It was previously marketed by Roche as a cough suppressant available in liquid form.[1][2][3]

See also

References

  1. ↑ PMID 15409516 (PMID 15409516)
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  2. ↑ PMID 18102053 (PMID 18102053)
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  3. ↑ PMID 3839404 (PMID 3839404)
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Template:Cough and cold preparations

Template:GABAAR PAMs


Template:Respiratory-system-drug-stub

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