Aprobarbital: Difference between revisions
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| verifiedrevid = 443395571 | | verifiedrevid = 443395571 | ||
| IUPAC_name = 5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione | | IUPAC_name = 5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione | ||
| image = Aprobarbital | | image = Aprobarbital.png | ||
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| synonyms = aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid | | synonyms = aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid | ||
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==Overview== | |||
'''Aprobarbital''' (as known in the [[United States]], or '''aprobarbitone''' (as known elsewhere), sold as '''Oramon''', '''Somnifaine''', and '''Allonal''', is a [[barbiturate]] derivative invented in the 1920s by Ernst Preiswerk. It has [[sedative]], [[hypnotic]] and [[anticonvulsant]] properties, and was used primarily for the treatment of [[insomnia]].<ref> Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81. </ref> Aprobarbital was never as widely used as more common barbiturate derivatives such as [[phenobarbital]] and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin. | '''Aprobarbital''' (as known in the [[United States]], or '''aprobarbitone''' (as known elsewhere), sold as '''Oramon''', '''Somnifaine''', and '''Allonal''', is a [[barbiturate]] derivative invented in the 1920s by Ernst Preiswerk. It has [[sedative]], [[hypnotic]] and [[anticonvulsant]] properties, and was used primarily for the treatment of [[insomnia]].<ref> Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81. </ref> Aprobarbital was never as widely used as more common barbiturate derivatives such as [[phenobarbital]] and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin. | ||
== References == | == References == | ||
{{reflist}} | {{reflist|2}} | ||
{{Barbiturates}} | {{Barbiturates}} | ||
{{Hypnotics and sedatives}} | {{Hypnotics and sedatives}} | ||
[[Category:Barbiturates]] | [[Category:Barbiturates]] | ||
[[Category:Alkenes]] | [[Category:Alkenes]] | ||
[[Category: | [[Category:Drug]] | ||
Latest revision as of 14:35, 13 April 2015
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| Clinical data | |
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| Synonyms | aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C10H14N2O3 |
| Molar mass | 210.23 g/mol |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Aprobarbital (as known in the United States, or aprobarbitone (as known elsewhere), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.[1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.
References
- ↑ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.