Sodium-glucose co-transporter 2: Difference between revisions
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'''Sodium-dependent glucose cotrasporter 2''' are a family of [[glucose transporter]] expressed in the luminal membrane of the [[proximal kidney tubule]]s. They contribute to [[renal glucose reabsorption]].{{ | {{protein | ||
| Name = solute carrier family 5 (sodium/glucose cotransporter), member 2 | |||
| caption = | |||
| image = | |||
| width = | |||
| HGNCid = 11037 | |||
| Symbol = SLC5A2 | |||
| AltSymbols = SGLT2 | |||
| EntrezGene = 6524 | |||
| OMIM = 182381 | |||
| RefSeq = NM_003041 | |||
| UniProt = P31639 | |||
| PDB = | |||
| ECnumber = | |||
| Chromosome = 16 | |||
| Arm = p | |||
| Band = 11.2 | |||
| LocusSupplementaryData = | |||
}} | |||
{{SI}} | |||
==Overview== | |||
'''Sodium-dependent glucose cotrasporter 2''' are a family of [[glucose transporter]] expressed in the luminal membrane of the [[proximal kidney tubule]]s. They contribute to [[renal glucose reabsorption]].<ref> Anonymous 2015, [http://www.nlm.nih.gov/cgi/mesh/2015/MB_cgi?term={{PAGENAME}} {{PAGENAME}}]. Medical Subject Headings. U.S. National Library of Medicine.</ref> | |||
==Pharmacology== | |||
===Inhibitors=== | |||
* Canagliflozin | |||
* Dapagliflozin | |||
* Empagliflozin | |||
* Gliflozin | |||
==References== | |||
<references/> | |||
==External links== | |||
* {{MeshName|Sodium-Glucose+Transporter+2}} | |||
{{Ion pumps}} | |||
{{Membrane transport proteins}} | |||
Revision as of 03:44, 29 September 2015
| solute carrier family 5 (sodium/glucose cotransporter), member 2 | |
|---|---|
| Identifiers | |
| Symbol | SLC5A2 |
| Alt. symbols | SGLT2 |
| Entrez | 6524 |
| HUGO | 11037 |
| OMIM | 182381 |
| RefSeq | NM_003041 |
| UniProt | P31639 |
| Other data | |
| Locus | Chr. 16 p11.2 |
Overview
Sodium-dependent glucose cotrasporter 2 are a family of glucose transporter expressed in the luminal membrane of the proximal kidney tubules. They contribute to renal glucose reabsorption.[1]
Pharmacology
Inhibitors
- Canagliflozin
- Dapagliflozin
- Empagliflozin
- Gliflozin
References
- ↑ Anonymous 2015, co-transporter 2 Sodium-glucose co-transporter 2. Medical Subject Headings. U.S. National Library of Medicine.
External links
- Sodium-Glucose+Transporter+2 at the US National Library of Medicine Medical Subject Headings (MeSH)