Dermoid cyst pathophysiology: Difference between revisions
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*Dermoid cyst arises from the ectoderm and are generally formed of skin, hair follicles, teeth and sebaceous glands.<ref name=bm>{{Citation |last=Joseph Schuetz |first=Maurice |last= Elsheikh |first=Tarik |year=2002 |title=Dermoid Cyst (Mature Cystic Teratoma) of the Cecum |publisher=Archives of Pathology & Laboratory Medicine |publication-place= Muncie, IN |page=97-99 |url=http://www.archivesofpathology.org/doi/full/10.1043/0003-9985%282002%29126%3C0097%3ADCMCTO%3E2.0.CO%3B2 |accessdate=February 2, 2016}}</ref> | *Dermoid cyst arises from the ectoderm and are generally formed of skin, hair follicles, teeth and sebaceous glands.<ref name=bm>{{Citation |last=Joseph Schuetz |first=Maurice |last= Elsheikh |first=Tarik |year=2002 |title=Dermoid Cyst (Mature Cystic Teratoma) of the Cecum |publisher=Archives of Pathology & Laboratory Medicine |publication-place= Muncie, IN |page=97-99 |url=http://www.archivesofpathology.org/doi/full/10.1043/0003-9985%282002%29126%3C0097%3ADCMCTO%3E2.0.CO%3B2 |accessdate=February 2, 2016}}</ref> | ||
*Dermoid cysts occur in the embryonic lines of fusion. The majority of cases are reported in the midline of the body, particularly in the ovaries and testis.<ref name="pmid21922020">{{cite journal| author=Makos C, Noussios G, Peios M, Gougousis S, Chouridis P| title=Dermoid cysts of the floor of the mouth: two case reports. | journal=Case Rep Med | year= 2011 | volume= 2011 | issue= | pages= 362170 | pmid=21922020 | doi=10.1155/2011/362170 | pmc=PMC3172983 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21922020 }} </ref> | *Dermoid cysts occur in the embryonic lines of fusion. The majority of cases are reported in the midline of the body, particularly in the ovaries and testis.<ref name="pmid21922020">{{cite journal| author=Makos C, Noussios G, Peios M, Gougousis S, Chouridis P| title=Dermoid cysts of the floor of the mouth: two case reports. | journal=Case Rep Med | year= 2011 | volume= 2011 | issue= | pages= 362170 | pmid=21922020 | doi=10.1155/2011/362170 | pmc=PMC3172983 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21922020 }} </ref> | ||
==Ovarian Dermoid Cysts== | |||
==Spinal Dermoid Cysts== | |||
*Spinal dermoid cysts arise from the embryonal ectodermal cells that are arrested within the spinal canal at the time of neural tube closure during development. <ref name="pmid23508636">{{cite journal| author=Sharma M, Mally R, Velho V| title=Ruptured conus medullaris dermoid cyst with fat droplets in the central canal [corrected]. | journal=Asian Spine J | year= 2013 | volume= 7 | issue= 1 | pages= 50-4 | pmid=23508636 | doi=10.4184/asj.2013.7.1.50 | pmc=PMC3596585 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23508636 }} </ref> | |||
*Spinal dermoid cysts are usually located in the lumbosacral region (60%) and rarely located in the upper thoracic (10%) and cervical regions (5%).<ref name="pmid17160798">{{cite journal| author=Altay H, Kitiş O, Calli C, Yünten N| title=A spinal dermoid tumor that ruptured into the subarachnoidal space and syrinx cavity. | journal=Diagn Interv Radiol | year= 2006 | volume= 12 | issue= 4 | pages= 171-3 | pmid=17160798 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17160798 }} </ref> | |||
==Intracranial Dermoid Cysts== | |||
*Intracranial dermoid cysts are usually located in the midline, although they can occur on any side. | |||
*The most common locations include: | |||
**Posterior fossa / vermis | |||
**Suprasellar/subfrontal | |||
===Dermoid cysts of the floor of the mouth=== | ===Dermoid cysts of the floor of the mouth=== | ||
Revision as of 14:59, 18 February 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Dermoid cyst arises from the ectodermal and are generally formed of skin, hair follicles, teeth and sebaceous glands.[1]
Pathophysiology
- Dermoid cyst arises from the ectoderm and are generally formed of skin, hair follicles, teeth and sebaceous glands.[1]
- Dermoid cysts occur in the embryonic lines of fusion. The majority of cases are reported in the midline of the body, particularly in the ovaries and testis.[2]
Ovarian Dermoid Cysts
Spinal Dermoid Cysts
- Spinal dermoid cysts arise from the embryonal ectodermal cells that are arrested within the spinal canal at the time of neural tube closure during development. [3]
- Spinal dermoid cysts are usually located in the lumbosacral region (60%) and rarely located in the upper thoracic (10%) and cervical regions (5%).[4]
Intracranial Dermoid Cysts
- Intracranial dermoid cysts are usually located in the midline, although they can occur on any side.
- The most common locations include:
- Posterior fossa / vermis
- Suprasellar/subfrontal
Dermoid cysts of the floor of the mouth
- The pathogenesis of dermoid cysts of the floor of the mouth is hypothesized into the following three theories:[2]
- Dermoid cysts of the floor of the mouth arise from the entrapped embryonic cells in the third or fourth week of embryonic life during the midline fusion of the first and second branchial arches.
- The second theory is that the acquired cysts may result from iatrogenic or traumatic implantation of the epithelial cells that subsequently grow.
- The last theory is that the cysts of the floor of the mouth are a thyroglossal anomaly with predominantly ectodermal components.
Gross pathology
- On gross pathology, uniloculated cysts lined by skin, containing sebaceous glands, hair follicles, and teeth are characteristic findings of dermoid cysts.[1]
References
- ↑ 1.0 1.1 1.2 Elsheikh, Tarik (2002), Dermoid Cyst (Mature Cystic Teratoma) of the Cecum, Muncie, IN: Archives of Pathology & Laboratory Medicine, p. 97-99, retrieved February 2, 2016
- ↑ 2.0 2.1 Makos C, Noussios G, Peios M, Gougousis S, Chouridis P (2011). "Dermoid cysts of the floor of the mouth: two case reports". Case Rep Med. 2011: 362170. doi:10.1155/2011/362170. PMC 3172983. PMID 21922020.
- ↑ Sharma M, Mally R, Velho V (2013). "Ruptured conus medullaris dermoid cyst with fat droplets in the central canal [corrected]". Asian Spine J. 7 (1): 50–4. doi:10.4184/asj.2013.7.1.50. PMC 3596585. PMID 23508636.
- ↑ Altay H, Kitiş O, Calli C, Yünten N (2006). "A spinal dermoid tumor that ruptured into the subarachnoidal space and syrinx cavity". Diagn Interv Radiol. 12 (4): 171–3. PMID 17160798.