Interleukin-28 receptor: Difference between revisions

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{{protein
{{infobox protein
| Name = [[interleukin 28 receptor, alpha subunit|interleukin 28 receptor, alpha (interferon, lambda receptor)]]
| Name = [[interleukin 28 receptor, alpha subunit|interleukin 28 receptor, alpha (interferon, lambda receptor)]]
| caption =  
| caption =  
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| LocusSupplementaryData =  
| LocusSupplementaryData =  
}}
}}
{{protein
{{infobox protein
| Name = [[Interleukin 10 receptor, beta subunit|interleukin 10 receptor, beta]]
| Name = [[Interleukin 10 receptor, beta subunit|interleukin 10 receptor, beta]]
| caption =  
| caption =  
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| LocusSupplementaryData =  
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}}
{{CMG}}
'''Interleukin-28 receptor''' is a [[type II cytokine receptor]]. It binds [[interleukin-28]]. It consists of an [[interleukin 28 receptor, alpha subunit|α]] and shares a common [[interleukin 10 receptor, beta subunit|β]] subunit with the [[interleukin-10 receptor]].<ref name="pmid12483210">{{cite journal |vauthors=Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP | title = IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex | journal = Nat. Immunol. | volume = 4 | issue = 1 | pages = 69–77 | year = 2003 | pmid = 12483210 | doi = 10.1038/ni875 }}</ref><ref name="pmid12469119">{{cite journal |vauthors=Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM | title = IL-28, IL-29 and their class II cytokine receptor IL-28R | journal = Nat. Immunol. | volume = 4 | issue = 1 | pages = 63–8 | year = 2003 | pmid = 12469119 | doi = 10.1038/ni873 }}</ref>
__NOTOC__
 
 
==Overview==
 
'''Interleukin-28 receptor''' is a [[type II cytokine receptor]]. It binds [[interleukin-28]]. It consists of an [[interleukin 28 receptor, alpha subunit|α]] and shares a common [[interleukin 10 receptor, beta subunit|β]] subunit the with [[interleukin-10 receptor]].<ref name="pmid12483210">{{cite journal | author = Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP | title = IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex | journal = Nat. Immunol. | volume = 4 | issue = 1 | pages = 69–77 | year = 2003 | pmid = 12483210 | doi = 10.1038/ni875 | issn = }}</ref><ref name="pmid12469119">{{cite journal | author = Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM | title = IL-28, IL-29 and their class II cytokine receptor IL-28R | journal = Nat. Immunol. | volume = 4 | issue = 1 | pages = 63–8 | year = 2003 | pmid = 12469119 | doi = 10.1038/ni873 | issn = }}</ref>


==References==
==References==
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* {{MeshName|Receptors,+Interleukin-28}}
* {{MeshName|Receptors,+Interleukin-28}}


{{Cytokine receptors}}
{{Cytokine receptor modulators}}
{{Interleukin receptor modulators}}


{{Immune receptors}}
[[Category:Cytokine receptors|1]]
[[Category:Type II cytokine receptors]]
[[Category:Type II cytokine receptors]]




{{WikiDoc Help Menu}}
{{membrane-protein-stub}}
{{WikiDoc Sources}}

Latest revision as of 18:36, 4 June 2016

interleukin 28 receptor, alpha (interferon, lambda receptor)
Identifiers
SymbolIL28RA
Alt. symbolsCRF2/12, IFNLR, IL-28R1
Entrez163702
HUGO18584
OMIM607404
RefSeqNM_170743
UniProtQ8IU57
Other data
LocusChr. 1 p36.11
interleukin 10 receptor, beta
Identifiers
SymbolIL10RB
Alt. symbolsCRFB4, D21S58, D21S66
Entrez3588
HUGO5965
OMIM123889
RefSeqNM_000628
UniProtQ08334
Other data
LocusChr. 21 q22.1-22.2

Interleukin-28 receptor is a type II cytokine receptor. It binds interleukin-28. It consists of an α and shares a common β subunit with the interleukin-10 receptor.[1][2]

References

  1. ↑ Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK, Langer JA, Sheikh F, Dickensheets H, Donnelly RP (2003). "IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex". Nat. Immunol. 4 (1): 69–77. doi:10.1038/ni875. PMID 12483210.
  2. ↑ Sheppard P, Kindsvogel W, Xu W, Henderson K, Schlutsmeyer S, Whitmore TE, Kuestner R, Garrigues U, Birks C, Roraback J, Ostrander C, Dong D, Shin J, Presnell S, Fox B, Haldeman B, Cooper E, Taft D, Gilbert T, Grant FJ, Tackett M, Krivan W, McKnight G, Clegg C, Foster D, Klucher KM (2003). "IL-28, IL-29 and their class II cytokine receptor IL-28R". Nat. Immunol. 4 (1): 63–8. doi:10.1038/ni873. PMID 12469119.

External links


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