DUSP22: Difference between revisions
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'''Dual specificity protein phosphatase 22''' is an [[enzyme]] that in humans is encoded by the ''DUSP22'' [[gene]].<ref name="pmid9205128">{{cite journal | vauthors = Smith A, Price C, Cullen M, Muda M, King A, Ozanne B, Arkinstall S, Ashworth A | title = Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7) | journal = Genomics | volume = 42 | issue = 3 | pages = 524–7 |date=Sep 1997 | pmid = 9205128 | pmc = | doi = 10.1006/geno.1997.4756 }}</ref><ref name="pmid11717427">{{cite journal | vauthors = Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK | title = Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1 | journal = Proc Natl Acad Sci U S A | volume = 98 | issue = 24 | pages = 13613–8 |date=Nov 2001 | pmid = 11717427 | pmc = 61089 | doi = 10.1073/pnas.231499098 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: DUSP22 dual specificity phosphatase 22| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56940| accessdate = }}</ref> | '''Dual specificity protein phosphatase 22''' is an [[enzyme]] that in humans is encoded by the ''DUSP22'' [[gene]].<ref name="pmid9205128">{{cite journal | vauthors = Smith A, Price C, Cullen M, Muda M, King A, Ozanne B, Arkinstall S, Ashworth A | title = Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7) | journal = Genomics | volume = 42 | issue = 3 | pages = 524–7 |date=Sep 1997 | pmid = 9205128 | pmc = | doi = 10.1006/geno.1997.4756 }}</ref><ref name="pmid11717427">{{cite journal | vauthors = Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK | title = Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1 | journal = Proc Natl Acad Sci U S A | volume = 98 | issue = 24 | pages = 13613–8 |date=Nov 2001 | pmid = 11717427 | pmc = 61089 | doi = 10.1073/pnas.231499098 | bibcode = 2001PNAS...9813613S }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: DUSP22 dual specificity phosphatase 22| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56940| accessdate = }}</ref> | ||
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==Interactions== | ==Interactions== | ||
DUSP22 has been shown to [[Protein-protein interaction|interact]] with [[MAPK1]]<ref name=pmid11346645>{{cite journal |last=Aoyama |first=K |author2=Nagata M |author3=Oshima K |author4=Matsuda T |author5=Aoki N |date=Jul 2001 |title=Molecular cloning and characterization of a novel dual specificity phosphatase, LMW-DSP2, that lacks the cdc25 homology domain |journal=J. Biol. Chem. |volume=276 |issue=29 |pages=27575–83 |publisher= |location = United States| issn = 0021-9258| pmid = 11346645 |doi = 10.1074/jbc.M100408200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[MAPK8]].<ref name=pmid11346645/> | DUSP22 has been shown to [[Protein-protein interaction|interact]] with [[MAPK1]]<ref name=pmid11346645>{{cite journal |last=Aoyama |first=K |author2=Nagata M |author3=Oshima K |author4=Matsuda T |author5=Aoki N |date=Jul 2001 |title=Molecular cloning and characterization of a novel dual specificity phosphatase, LMW-DSP2, that lacks the cdc25 homology domain |journal=J. Biol. Chem. |volume=276 |issue=29 |pages=27575–83 |publisher= |location = United States| issn = 0021-9258| pmid = 11346645 |doi = 10.1074/jbc.M100408200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=3757226}}</ref> and [[MAPK8]].<ref name=pmid11346645/> | ||
==References== | ==References== | ||
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*{{cite journal | vauthors=Aoyama K, Nagata M, Oshima K |title=Molecular cloning and characterization of a novel dual specificity phosphatase, LMW-DSP2, that lacks the cdc25 homology domain. |journal=J. Biol. Chem. |volume=276 |issue= 29 |pages= 27575–83 |year= 2001 |pmid= 11346645 |doi= 10.1074/jbc.M100408200 |display-authors=etal}} | *{{cite journal | vauthors=Aoyama K, Nagata M, Oshima K |title=Molecular cloning and characterization of a novel dual specificity phosphatase, LMW-DSP2, that lacks the cdc25 homology domain. |journal=J. Biol. Chem. |volume=276 |issue= 29 |pages= 27575–83 |year= 2001 |pmid= 11346645 |doi= 10.1074/jbc.M100408200 |display-authors=etal|pmc=3757226 }} | ||
*{{cite journal | vauthors=Alonso A, Merlo JJ, Na S |title=Inhibition of T cell antigen receptor signaling by VHR-related MKPX (VHX), a new dual specificity phosphatase related to VH1 related (VHR). |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5524–8 |year= 2002 |pmid= 11733513 |doi= 10.1074/jbc.M107653200 |display-authors=etal}} | *{{cite journal | vauthors=Alonso A, Merlo JJ, Na S |title=Inhibition of T cell antigen receptor signaling by VHR-related MKPX (VHX), a new dual specificity phosphatase related to VH1 related (VHR). |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5524–8 |year= 2002 |pmid= 11733513 |doi= 10.1074/jbc.M107653200 |display-authors=etal}} | ||
*{{cite journal | vauthors=Chen AJ, Zhou G, Juan T |title=The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway. |journal=J. Biol. Chem. |volume=277 |issue= 39 |pages= 36592–601 |year= 2002 |pmid= 12138158 |doi= 10.1074/jbc.M200453200 |display-authors=etal}} | *{{cite journal | vauthors=Chen AJ, Zhou G, Juan T |title=The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway. |journal=J. Biol. Chem. |volume=277 |issue= 39 |pages= 36592–601 |year= 2002 |pmid= 12138158 |doi= 10.1074/jbc.M200453200 |display-authors=etal}} | ||
*{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}} | *{{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }} | ||
*{{cite journal | vauthors=Mungall AJ, Palmer SA, Sims SK |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |display-authors=etal}} | *{{cite journal | vauthors=Mungall AJ, Palmer SA, Sims SK |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |display-authors=etal}} | ||
*{{cite journal | vauthors=Alonso A, Narisawa S, Bogetz J |title=VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX. |journal=J. Biol. Chem. |volume=279 |issue= 31 |pages= 32586–91 |year= 2004 |pmid= 15138252 |doi= 10.1074/jbc.M403442200 |display-authors=etal}} | *{{cite journal | vauthors=Alonso A, Narisawa S, Bogetz J |title=VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX. |journal=J. Biol. Chem. |volume=279 |issue= 31 |pages= 32586–91 |year= 2004 |pmid= 15138252 |doi= 10.1074/jbc.M403442200 |display-authors=etal}} | ||
Latest revision as of 07:30, 23 June 2018
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Dual specificity protein phosphatase 22 is an enzyme that in humans is encoded by the DUSP22 gene.[1][2][3]
Interactions
DUSP22 has been shown to interact with MAPK1[4] and MAPK8.[4]
References
- ↑ Smith A, Price C, Cullen M, Muda M, King A, Ozanne B, Arkinstall S, Ashworth A (Sep 1997). "Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7)". Genomics. 42 (3): 524–7. doi:10.1006/geno.1997.4756. PMID 9205128.
- ↑ Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK (Nov 2001). "Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1". Proc Natl Acad Sci U S A. 98 (24): 13613–8. Bibcode:2001PNAS...9813613S. doi:10.1073/pnas.231499098. PMC 61089. PMID 11717427.
- ↑ "Entrez Gene: DUSP22 dual specificity phosphatase 22".
- ↑ 4.0 4.1 Aoyama, K; Nagata M; Oshima K; Matsuda T; Aoki N (Jul 2001). "Molecular cloning and characterization of a novel dual specificity phosphatase, LMW-DSP2, that lacks the cdc25 homology domain". J. Biol. Chem. United States. 276 (29): 27575–83. doi:10.1074/jbc.M100408200. ISSN 0021-9258. PMC 3757226. PMID 11346645.
Further reading
- Aoyama K, Nagata M, Oshima K, et al. (2001). "Molecular cloning and characterization of a novel dual specificity phosphatase, LMW-DSP2, that lacks the cdc25 homology domain". J. Biol. Chem. 276 (29): 27575–83. doi:10.1074/jbc.M100408200. PMC 3757226. PMID 11346645.
- Alonso A, Merlo JJ, Na S, et al. (2002). "Inhibition of T cell antigen receptor signaling by VHR-related MKPX (VHX), a new dual specificity phosphatase related to VH1 related (VHR)". J. Biol. Chem. 277 (7): 5524–8. doi:10.1074/jbc.M107653200. PMID 11733513.
- Chen AJ, Zhou G, Juan T, et al. (2002). "The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathway". J. Biol. Chem. 277 (39): 36592–601. doi:10.1074/jbc.M200453200. PMID 12138158.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
- Alonso A, Narisawa S, Bogetz J, et al. (2004). "VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX". J. Biol. Chem. 279 (31): 32586–91. doi:10.1074/jbc.M403442200. PMID 15138252.
- Fortna A, Kim Y, MacLaren E, et al. (2004). "Lineage-specific gene duplication and loss in human and great ape evolution". PLoS Biol. 2 (7): E207. doi:10.1371/journal.pbio.0020207. PMC 449870. PMID 15252450.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Yokota T, Nara Y, Kashima A, et al. (2007). "Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution". Proteins. 66 (2): 272–8. doi:10.1002/prot.21152. PMID 17068812.
- Sekine Y, Ikeda O, Hayakawa Y, et al. (2007). "DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118". Oncogene. 26 (41): 6038–49. doi:10.1038/sj.onc.1210426. PMID 17384676.
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