Dermoid cyst pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Dermoid cyst arises from the ectodermal and are generally formed of skin, hair follicles, teeth and sebaceous glands.[1]
Pathophysiology
- Dermoid cyst arises from the ectoderm and are generally formed of skin, hair follicles, teeth and sebaceous glands.[1]
- Dermoid cysts occur in the embryonic lines of fusion. The majority of cases are reported in the midline of the body, particularly in the ovaries and testis.[2]
Dermoid cysts of the floor of the mouth
- The pathogenesis of dermoid cysts of the floor of the mouth is hypothesized into the following three theories:[2]
- Dermoid cysts of the floor of the mouth arise from the entrapped embryonic cells in the third or fourth week of embryonic life during the midline fusion of the first and second branchial arches.
- The second theory is that the acquired cysts may result from iatrogenic or traumatic implantation of the epithelial cells that subsequently grow.
- The last theory is that the cysts of the floor of the mouth are a thyroglossal anomaly with predominantly ectodermal components.
Gross pathology
- On gross pathology, uniloculated cysts lined by skin, containing sebaceous glands, hair follicles, and teeth are characteristic findings of dermoid cysts.[1]
References
- ↑ 1.0 1.1 1.2 Elsheikh, Tarik (2002), Dermoid Cyst (Mature Cystic Teratoma) of the Cecum, Muncie, IN: Archives of Pathology & Laboratory Medicine, p. 97-99, retrieved February 2, 2016
- ↑ 2.0 2.1 Makos C, Noussios G, Peios M, Gougousis S, Chouridis P (2011). "Dermoid cysts of the floor of the mouth: two case reports". Case Rep Med. 2011: 362170. doi:10.1155/2011/362170. PMC 3172983. PMID 21922020.