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Cyclin-dependent kinase (CDC2-like) 10, also known as CDK10, is a human gene.[1]
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase. At least three alternatively spliced transcript variants encoding different isoforms have been reported, two of which contain multiple non-AUG translation initiation sites.[1]
Li S, MacLachlan TK, De Luca A; et al. (1995). "The cdc-2-related kinase, PISSLRE, is essential for cell growth and acts in G2 phase of the cell cycle". Cancer Res. 55 (18): 3992–5. PMID7664269.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Bullrich F, MacLachlan TK, Sang N; et al. (1995). "Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer". Cancer Res. 55 (6): 1199–205. PMID7882308.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Brambilla R, Draetta G (1994). "Molecular cloning of PISSLRE, a novel putative member of the cdk family of protein serine/threonine kinases". Oncogene. 9 (10): 3037–41. PMID8084611.
Graña X, Claudio PP, De Luca A; et al. (1994). "PISSLRE, a human novel CDC2-related protein kinase". Oncogene. 9 (7): 2097–103. PMID8208557.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID8889548.CS1 maint: Multiple names: authors list (link)
Crawford J, Ianzano L, Savino M; et al. (1999). "The PISSLRE gene: structure, exon skipping, and exclusion as tumor suppressor in breast cancer". Genomics. 56 (1): 90–7. doi:10.1006/geno.1998.5676. PMID10036189.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Sergère JC, Thuret JY, Le Roux G; et al. (2000). "Human CDK10 gene isoforms". Biochem. Biophys. Res. Commun. 276 (1): 271–7. doi:10.1006/bbrc.2000.3395. PMID11006117.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID11076863.CS1 maint: Multiple names: authors list (link)
Kasten M, Giordano A (2001). "Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity". Oncogene. 20 (15): 1832–8. doi:10.1038/sj.onc.1204295. PMID11313931.
Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID15489336.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID16381901.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
Wissing J, Jänsch L, Nimtz M; et al. (2007). "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry". Mol. Cell Proteomics. 6 (3): 537–47. doi:10.1074/mcp.T600062-MCP200. PMID17192257.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
