Aprobarbital

Aprobarbital
	File:Aprobarbital Structural Formulae.svg
Clinical data
Synonyms	aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid
AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	N05CA05 (WHO) ;
Identifiers
	IUPAC name 5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione;
CAS Number	77-02-1 ;
PubChem CID	6464;
DrugBank	DB01352 ;
ChemSpider	6221 ;
UNII	Q0YKG9L6RF;
KEGG	D00698 ;
ChEBI	CHEBI:2791 ;
ChEMBL	ChEMBL7863 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C10H14N2O3
Molar mass	210.23 g/mol
3D model (JSmol)	Interactive image;
	SMILES O=C1NC(=O)NC(=O)C1(C(C)C)C\C=C;
	InChI InChI=1S/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15) ; Key:UORJNBVJVRLXMQ-UHFFFAOYSA-N ;
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Aprobarbital (as known in the United States, or aprobarbitone (as known elsewhere), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.^[1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.

References

↑ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.

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Template:GABAAR PAMs

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[1] Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.

[1]

Aprobarbital

References

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