KCNK6

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Potassium channel subfamily K member 6 is a protein that in humans is encoded by the KCNK6 gene.

This gene encodes K_2P6.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. K_2P6.1, considered an open rectifier, is widely expressed. It is stimulated by arachidonic acid, and inhibited by internal acidification and volatile anaesthetics.

See also

• Tandem pore domain potassium channel

Further reading

• Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (2001). "Potassium leak channels and the KCNK family of two-P-domain subunits". Nat. Rev. Neurosci. 2 (3): 175–84. doi:10.1038/35058574. PMID 11256078.
• Mahboubi S, Kaufmann JH (1978). "Intramural duodenal hematoma in children. The role of the radiologist in its conservative management". Gastrointestinal radiology. 1 (2): 167–71. PMID 1088718.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Salinas M, Reyes R, Lesage F, et al. (1999). "Cloning of a new mouse two-P domain channel subunit and a human homologue with a unique pore structure". J. Biol. Chem. 274 (17): 11751–60. doi:10.1074/jbc.274.17.11751. PMID 10206991.
• Pountney DJ, Gulkarov I, Vega-Saenz de Miera E, et al. (1999). "Identification and cloning of TWIK-originated similarity sequence (TOSS): a novel human 2-pore K+ channel principal subunit". FEBS Lett. 450 (3): 191–6. doi:10.1016/S0014-5793(99)00495-0. PMID 10359073.
• Patel AJ, Maingret F, Magnone V, et al. (2000). "TWIK-2, an inactivating 2P domain K+ channel". J. Biol. Chem. 275 (37): 28722–30. doi:10.1074/jbc.M003755200. PMID 10887187.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mhatre AN, Li J, Chen AF, et al. (2004). "Genomic structure, cochlear expression, and mutation screening of KCNK6, a candidate gene for DFNA4". J. Neurosci. Res. 75 (1): 25–31. doi:10.1002/jnr.10839. PMID 14689445.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• KCNK6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.